Knowledge of Oral Cancer among Online Respondent General Dentists: A Cross-sectional Survey.

Introduction: Oral cancer is a worldwide medical issue with expanding paces of occurrence and rising mortality rates. Oral cancer is the sixth most common cancer in Nepal with a prevalence of 4.6%.

Calcifying Epithelial Odontogenic Tumor: A Case Report.

Calcifying epithelial odontogenic tumor is a rare benign odontogenic tumor which accounts for approximately 1% of the entire odontogenic tumor. It was firstly described by Pindborg, and thus, is also referred to as the "Pindborg tumor". Histologically, Pindborg tumor consists of three distinct histological compo-nents: sheets of polyhedral epithelial cells, amyloid like deposits, and calcifications.

Glandular Odontogenic Cyst in Maxilla: A Case Series.

Glandular odontogenic cyst is rare phenomenon with 0.012% to 0.03% frequency of all jaw cysts and worldwide prevalence of 0.

Oral Cancer Knowledge and Awareness in Patients Visiting Kantipur Dental College.

Background: Lack of knowledge and awareness about oral cancer, its risk factors and negligence of the early warning signs play crucial role in raising the incidence of the disease. The present study was carried out to evaluate the awareness of oral cancer among patients visiting Kantipur Dental College, Kathmandu, Nepal.

Methods: The cross-sectional study was done in 471 patients from 15-85 years.

Prevalence of Oral Mucosal Lesions in a Tertiary Care Dental Hospital of Kathmandu.

Introduction: Oral mucosa can be affected by a variety of soft tissue lesions and conditions. Benign as well as malignant lesions of oral cavity are common. Squamous cell carcinoma is one of the commonest malignancies.

May High MMP-2 and TIMP-2 Expressions Increase or Decrease the Aggressivity of Oral Cancer?

Matrix metalloproteinases-2 (MMP-2) and the tissue inhibitor of metalloproteinase-2 (TIMP-2), may presumably have an important role on the invasion and metastatic spread of malignancies attributed to an uncontrolled degradation of the extracellular matrix (ECM). A retrospective chart analysis was carried out to study the expression of MMP-2 and TIMP-2 on the archival samples of oral squamous cell carcinoma (OSCC) (n = 30) and normal mucosa (n = 10) by immunohistochemistry and compared with the clinicopathologic parameters of cases. Both MMP-2 and TIMP-2 expressions showed a positive correlation with the grades, stages and metastatic capacities of tumors (Spearman's correlation, p < 0.

Immunohistochemical correlation of matrix metalloproteinase-2 and tissue inhibitors of metalloproteinase-2 in tobacco associated epithelial dysplasia.

Aim: To study the immunohistochemical expression of matrix metalloproteinase and tissue inhibitors of matrix metalloproteinase-2 in different histological grades of tobacco associated epithelial dysplasia and correlate the association between these proteases. Potentially malignant oral disorders (PMODs) progressing to oral cancer are related to the severity of epithelial dysplasia.

Methods: A retrospective immunohistochemical study was carried out on 30 clinically and histologically proven cases of leukoplakia with dysplasia and 10 cases of normal buccal mucosa using anti-MMP-2 and anti-TIMP-2 monoclonal antibodies.