Role of serum interleukin-6 in comparing surgical stress after laparoscopic-assisted vaginal hysterectomy and non-descent vaginal hysterectomy for large uteri.

Aims And Objectives: To compare the perioperative inflammatory response using interleukin-6 (IL-6) in patients of laparoscopic-assisted vaginal hysterectomy (LAVH) and non-descent vaginal hysterectomy (NDVH) for large uteri with benign disease.

Materials And Methods: Twenty women with benign uterine disease and failed medical management with size of uterus ranging from 300 to 1,500 g (12-24 weeks) were randomized into two equal groups for either technique of hysterectomy, LAVH and NDVH. Venous blood levels of IL-6 were measured preoperatively and 3, 24 and 72 h after beginning of surgery.