Exploring the role of macromolecular crowding and TNFR1 in cell volume control.

The excessive cosolute densities in the intracellular fluid create a physicochemical condition called macromolecular crowding (MMC). Intracellular MMC entropically maintains the biochemical thermodynamic equilibria by favoring associative reactions while hindering transport processes. Rapid cell volume shrinkage during extracellular hypertonicity elevates the MMC and disrupts the equilibria, potentially ushering cell death.

Niche partitioning and host specialisation in fish-parasitising isopods: Trait-dependent patterns from three ecosystems on the east coast of India.

Due to their large size and obligate nature, Cymothoid isopods inflict a high degree of tissue damage to fish. Still, they are understudied at an ecosystem level despite their global presence and ecological role. In this work, we collected fish host-isopod parasite data, along with their life history and ecological traits, from the northern part of the east coast of India and investigated patterns in host specialisation and preference of isopod parasites using a trait-based network perspective.

High segregation and diminished global integration in large-scale brain functional networks enhances the perceptual binding of cross-modal stimuli.

Speech perception requires the binding of spatiotemporally disjoint auditory-visual cues. The corresponding brain network-level information processing can be characterized by two complementary mechanisms: functional segregation which refers to the localization of processing in either isolated or distributed modules across the brain, and integration which pertains to cooperation among relevant functional modules. Here, we demonstrate using functional magnetic resonance imaging recordings that subjective perceptual experience of multisensory speech stimuli, real and illusory, are represented in differential states of segregation-integration.

A new species of conger eel, Ariosoma (Congridae: Bathymyrinae), from the Bay of Bengal, India.

Ariosoma bengalense sp. nov. is described on the basis of two specimens having total length (TL) 216304 mm, collected from the northern part of the Bay of Bengal, India.

A new congrid eel, Rhynchoconger randalli sp. nov. (Congridae: Anguilliformes), with a pentagonal pattern of vomer dentition from the Bay of Bengal, Indian waters.

A new species Rhynchoconger randalli sp. nov. is described herein on the basis of 2 specimens collected from Paradeep fishing harbor, Odisha, India along the Bay of Bengal from a depth of about 3640 meters.

Enhanced top-down sensorimotor processing in somatic anxiety.

Functional neuroimaging research on anxiety has traditionally focused on brain networks associated with the psychological aspects of anxiety. Here, instead, we target the somatic aspects of anxiety. Motivated by the growing appreciation that top-down cortical processing plays a crucial role in perception and action, we used resting-state functional MRI data from the Human Connectome Project and Dynamic Causal Modeling (DCM) to characterize effective connectivity among hierarchically organized regions in the exteroceptive, interoceptive, and motor cortices.

Infection of the parasitic isopods on commercial fishes of the northern part of the east coast of India.

Unlabelled: The present study reports the parasitic isopod infection on commercial fishes of the northern part of the east coast of India collected during the period 2010-2015 from the marine waters of Odisha and West Bengal. During the study, 394 isopods were collected after examining 2668 fishes. These include 14 species of isopods, out of which 13 belong to 5 genera under the family Cymothoidae, and a single species belongs to the family: Aegidae.

A new Congrid eel, Rhynchoconger smithi sp. nov. (Anguilliformes: Congridae), from the Bay of Bengal, India.

A new Conger eel species is described based on four specimens collected from Petuaghat fishing harbour, West Bengal, India. The combination of morphological characters and molecular data are discordant with the seven congeners currently recognized. Rhynchoconger smithi sp.

Altered effective connectivity in sensorimotor cortices is a signature of severity and clinical course in depression.

Functional neuroimaging research on depression has traditionally targeted neural networks associated with the psychological aspects of depression. In this study, instead, we focus on alterations of sensorimotor function in depression. We used resting-state functional MRI data and dynamic causal modeling (DCM) to assess the hypothesis that depression is associated with aberrant effective connectivity within and between key regions in the sensorimotor hierarchy.

A new species of the genus Cirrhimuraena (Anguilliformes: Ophichthidae) from the Bay of Bengal, India.

A new species of the genus Cirrhimuraena (Anguilliformes: Ophichthidae), Cirrhimuraena indica sp. nov., is described based on eight specimens collected from the Paradip (Odisha) and Petuaghat harbours (West Bengal) along the Bay of Bengal.

Ophichthus kailashchandrai sp. nov. (Anguilliformes: Ophichthidae): a new species of snake eel from Indian waters, Bay of Bengal.

A new snake eel (Anguilliformes: Ophichthidae: Ophichthinae) species, Ophichthus kailashchandrai sp. nov., is described from three specimens, collected from the Shankarpur fishing harbour located on the northern part of the Bay of Bengal, West Bengal, India.

Changing clinico-epidemiology of post-kala-azar dermal leishmaniasis (PKDL) in India: Results of a survey in four endemic states.

Background & Objectives: Detection and treatment of post-kala-azar dermal leishmaniasis (PKDL) cases is considered important for kala-azar elimination. The objective of our study was to find out the proportion of different forms of lesions, interruption of treatment and rate of treatment completion, cure rates of PKDL, risk factors for developing severe forms of PKDL and utilization of services offered by the kala-azar elimination program.

Methods: A cross-sectional survey of PKDL patients registered for treatment at all levels of care during 2015 and 2016 was done.

Large-scale Functional Integration, Rather than Functional Dissociation along Dorsal and Ventral Streams, Underlies Visual Perception and Action.

Visual dual-stream theory posits that two distinct neural pathways of specific functional significance originate from primary visual areas and reach the inferior temporal (ventral) and posterior parietal areas (dorsal). However, there are several unresolved questions concerning the fundamental aspects of this theory. For example, is the functional dissociation between ventral and dorsal stream driven by features in input stimuli or is it driven by categorical differences between visuoperceptual and visuomotor functions? Is the dual stream rigid or flexible? What is the nature of the interactions between the two streams? We addressed these questions using fMRI recordings on healthy human volunteers and employing stimuli and tasks that can tease out the divergence between visuoperceptual and visuomotor variants of dual-stream theory.

Ophichthus johnmccoskeri sp. nov. (Anguilliformes: Ophichthidae): a new snake eel from Indian waters, Bay of Bengal.

A new species of snake eel (Anguilliformes: Ophichthidae: Ophichthinae), Ophichthus johnmccoskeri sp. nov., is described from three specimens collected from the northern part of the Bay of Bengal, India.

Neural Substrate of Group Mental Health: Insights from Multi-Brain Reference Frame in Functional Neuroimaging.

Contemporary mental health practice primarily centers around the neurobiological and psychological processes at the individual level. However, a more careful consideration of interpersonal and other group-level attributes (e.g.

An evaluation of planarity of the spatial QRS loop by three dimensional vectorcardiography: Its emergence and loss.

Aims: To objectively characterize and mathematically justify the observation that vectorcardiographic QRS loops in normal individuals are more planar than those from patients with ST elevation myocardial infarction (STEMI).

Methods: Vectorcardiograms (VCGs) were constructed from three simultaneously recorded quasi-orthogonal leads, I, aVF and V (sampled at 1000 samples/s). The planarity of these QRS loops was determined by fitting a surface to each loop.

A new species of elongate unpatterned moray eel of the genus Gymnothorax (Muraenidae: Muraeninae) from the Bay of Bengal.

An elongate, brown unpatterned moray eel, Gymnothorax indicus sp. nov., is described based on four specimens collected from the northern Bay of Bengal.

A new species of Short Brown Unpatterned Moray Eel of the Genus Gymnothorax (Anguilliformes: Muraenidae) from the Bay of Bengal.

A new species of short brown unpatterned moray eel of the genus Gymnothorax, Gymnothorax mishrai sp. nov. is described from a specimen of 324 mm total length, collected from the Bay of Bengal.

A new fish species of the Genus Hapalogenys (Perciformes: Hapalogenyidae) from the Bay of Bengal, India.

A new species of the genus Hapalogenys, Hapalogenys bengalensis sp. nov. is described from fourteen specimens collected from the Bay of Bengal coast.