Formulation of Transliposomal Nanocarrier Gel Containing Strychnine for the Effective Management of Skin Cancer.

Strychnine (STCN) has demonstrated an exceptional anticancer effect against various cancers. However, the STCN clinical utility has been hampered by its low water solubility, restricted therapeutic window, short half-life, and significant toxicity. The objective of this investigation was to design and optimize a formulation of strychnine-loaded transliposomes (STCN-TLs) for dermal administration of STCN to treat skin cancer.

Combinatorial drug-loaded quality by design adapted transliposome gel formulation for dermal delivery: In vitro and dermatokinetic study.

Background: Ursolic acid is a powerful drug that possesses many therapeutic properties, such as hepatoprotection, immunomodulation, anti-inflammatory, antidiabetic, antibacterial, antiviral, antiulcer, and anticancer activity. Centella asiatica (L.) Urban (Umbelliferae) contains a triterpene called asiatic acid, which has been used effectively in traditional Chinese and Indian medicine system for centuries.

Electrochemical study on the effect of polar and non-polar extract of on the corrosion inhibition of mild-steel in an acidic medium.

Electrochemical methods were used to characterize the inhibition efficacy of the extract of the high-altitude plant as an environmentally acceptable inhibitor for mild steel in 1.0 M HSO. The was extracted in hexane and methanol separately and applied on mild steel (MS) as an inhibitor.

Phytoconstituents-loaded nanomedicines for the management of acne.

Background: According to epidemiological data, a large percentage (80-90%) of adolescents suffer from acne vulgaris and approximately 30% of them need treatment. Possible outcomes of the inflammatory acne lesions are acne scars which, although they can be treated in several ways, may have a negative psychological impact on social life and relationships. There are three levels of acne: mild, moderate, and severe.

Myco-remediation: A mechanistic understanding of contaminants alleviation from natural environment and future prospect.

Industrialization and modernization of agricultural systems contaminated lithosphere, hydrosphere, and biosphere of the Earth. Sustainable remediation of contamination is essential for environmental sustainability. Myco-remediation is proposed to be a green, economical, and efficient technology over conventional remediation technologies to combat escalating pollution problems at a global scale.

Trace level monitoring of Cu(II) ion using CuS particles based membrane electrochemical sensor.

Cu(II) monitoring is a matter of great interest to researchers due to its toxicity and adverse environmental effects. Among different methods for detecting Cu(II), ion-selective electrode (ISE) is more advantageous as they are low-cost, easy to fabricate, and highly selective. Here, we report a simple, inexpensive, and reproducible procedure for the fabrication of Cu(II) ion-selective electrodes using CuS particles and polyvinyl chloride (PVC) as a matrix.

3D printing technology in healthcare: applications, regulatory understanding, IP repository and clinical trial status.

Mass consumerization of three-dimensional (3D) printing innovation has revolutionised admittance of 3D-printing in an expansive scope of ventures. When utilised predominantly for industrial manufacturing, 3D-printing strategies have rapidly attained acquaintance in different parts of health care industry. 3D-printing is a moderately new technology that has discovered promising applications in the medication conveyance and clinical areas.

Circular economy fertilization: Phycoremediated algal biomass as biofertilizers for sustainable crop production.

There is an urgent need to meet the demand of water and nutrients by their reuse and recycling to gratify sustainable food production system and resource conservation. Chlorella minutissima was found to be very effective in the removal of electrical conductivity (EC), total dissolved solids, phosphorous (P), potassium (K), ammonium, nitrate, biological oxygen demand (BOD) and chemical oxygen demand (COD) of sewage wastewater. We tested the effects of phycoremediated algal biomass addition to soil in field plots of baby corn and spinach, on plant growth, yield and soil chemical properties.

Dataset for the selection of electrolytes for Electropolymerization of aniline.

The most investigated conducting polymer (CP) is polyaniline (PANI)), a promising polymer due to its excellent environmental stability, simplicity of synthesis, and high electrical conductivity [1], [2], [3], [4]. In corrosion protection applications, the PANI film has shown promising potential in protecting active metals such as iron by acting as physical barrier coatings, as a primer layer and as component in a multi-layer coating system [5]. The PANI has an excellent potential to replace the toxic metal, such as chromates, in corrosion protection and is considered a green anti-corrosion candidate [5], [6], [7].

Nickel in terrestrial biota: Comprehensive review on contamination, toxicity, tolerance and its remediation approaches.

Nickel (Ni) has been a subject of interest for environmental, physiological, biological scientists due to its dual effect (toxicity and essentiality) in terrestrial biota. In general, the safer limit of Ni is 1.5 μg g in plants and 75-150 μg g in soil.

Quality by design (Qbd) assisted development of phytosomal gel of aloe vera extract for topical delivery.

The aim of the current study was to develop the phytosomal gel of aloe vera extract for improved topical delivery. Aloe vera extract loaded phytosomal system was developed by fixing the amount of aloe vera extract and ethanol and by varying the concentration of lecithin (0.15-0.

Lead Toxicity: Health Hazards, Influence on Food Chain, and Sustainable Remediation Approaches.

Lead (Pb) toxicity has been a subject of interest for environmental scientists due to its toxic effect on plants, animals, and humans. An increase in several Pb related industrial activities and use of Pb containing products such as agrochemicals, oil and paint, mining, etc. can lead to Pb contamination in the environment and thereby, can enter the food chain.

Methane production, oxidation and mitigation: A mechanistic understanding and comprehensive evaluation of influencing factors.

Methane is one of the critical greenhouse gases, which absorb long wavelength radiation, affects the chemistry of atmosphere and contributes to global climate change. Rice ecosystem is one of the major anthropogenic sources of methane. The anaerobic waterlogged soil in rice field provides an ideal environment to methanogens for methanogenesis.