Publications by authors named "Diong Nguk Chai"

Background: The standard treatment for thymomatous myasthenia gravis (TMG) patients is thymectomy, whereas its role in non-TMG (NTMG) is still under debate. The objective of this study is to assess myasthenia gravis (MG) outcomes of thymectomy using the uniportal video-assisted thoracoscopic surgery (UVATS) technique for both groups and evaluate the procedure's efficacy and safety.

Methods: We retrospectively collected data from January 2019 to December 2022 at Hospital Kuala Lumpur.

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Extensive chest wall tumor resection and reconstruction possess a formidable challenge and require good collaboration between thoracic and reconstructive surgeons. In this article, we reviewed our experience in six consecutive cases requiring complex chest wall resection and reconstruction with titanium rib plates and free anterolateral thigh fasciocutaneous flap with fascia lata with a minimum 24 months follow-up postoperatively. Six patients with a mean age of 54 were diagnosed to have locally advanced malignant (  = 5) and benign (  = 1) tumors.

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Article Synopsis
  • The study evaluates the survival benefits of lung surgery in patients with initially unresectable non-small cell lung cancer (NSCLC) after treatment with tyrosine kinase inhibitors (TKIs), focusing on those with tumor regression or regrowth.
  • Out of 32 patients analyzed, 19 underwent video-assisted lung surgery following TKI treatment, resulting in a 3-year overall survival rate of 61.5% and a 2-year progression-free survival rate of 43.9%.
  • The findings suggest that lung surgery is both feasible and safe, improving patient survival, and should be considered a part of treatment for initially unresectable NSCLC.
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Chest wall resection is defined as partial or full-thickness removal of the chest wall. Significant morbidity has been recorded, with documented respiratory failure as high as 27%. Medical records of all patients who had undergone chest wall resection and reconstruction were reviewed.

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Mediastinal nonseminomatous germ cell tumor (NSGCT) is rare. NSGCT shows excellent response to cisplatin-based chemotherapy. However, some tumors continue to enlarge despite normal tumor markers after chemotherapy, a rare condition called growing teratoma syndrome (GTS).

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