Publications by authors named "Diogo Oliveira Toledo"

Background & Aims: Survivors of critical illness experience significant skeletal muscle wasting that may predict clinical outcome. Ultrasound (US) is a noninvasive method that can measure muscle quadriceps muscle layer thickness (QMLT) at the bedside. The aim of this study was to determine the muscle loss assessed by ultrasonography (US) of the quadriceps femoris muscle in critically ill patients on mechanical ventilation and its relationship with hospital outcomes.

View Article and Find Full Text PDF

Introduction And Objective: Due to the high cost and insufficient offer, the request for Intensive Care (ICU) beds for postoperative recovery needs adequate criteria. Therefore, we studied the characteristics of patients referred to postoperative care at an ICU from the perspective of anesthesiologists, surgeons, and intensive care physicians.

Methods: A questionnaire on referrals to postoperative intensive care was applied to physicians at congresses in Brazil.

View Article and Find Full Text PDF

Background: Malnutrition is highly prevalent in hospitalized patients but seldom recognized and treated. Malnutrition poses several adverse events, such as increased infection rates, length of hospital stay, and mortality, as well as costs. Early nutrition interventions have been shown to decrease the associated malnutrition burdens, leading to relevant savings.

View Article and Find Full Text PDF

Background And Aims: Patients with hemodynamic instability need to receive intensive treatment as fluid replacement and vasoactive drugs. In the meantime, it is supposed to initiate nutritional therapy within 24 to 48 hours after admission to the intensive care unit (ICU), as an essential part of patient's intensive care and better outcomes. However, there are many controversies tangential to the prescription of enteral nutrition (EN) concomitant to the use of vasopressor and its doses.

View Article and Find Full Text PDF

Objective: The aim of this study was to evaluate the relevance of ultrasonography training by non-experts carrying out quadriceps muscle mass assessment.

Methods: Two non-expert evaluators were trained by two radiologists on the basic principles of ultrasonography and quadriceps muscle measurements. Afterward, they performed assessments on 30 healthy volunteers to determine interobserver agreement, considering two landmarks (two-thirds of the femoral distance, and 10 cm above the patella), which were tested by the intraclass correlation coefficient (ICC).

View Article and Find Full Text PDF
Article Synopsis
  • - Interest in non-invasive body composition assessment methods is increasing in health care due to their link to clinical outcomes, with technologies like computed tomography being particularly noted for studies in cancer and sarcopenia.
  • - Various methods such as bedside ultrasonography, bioelectrical impedance analysis, and dual x-ray absorptiometry offer accurate measurements of skeletal muscle mass, adipose tissue, and edema, helping to diagnose conditions like malnutrition.
  • - Understanding the pros and cons of each assessment technique is crucial for effective clinical application, as discussed in this review of relevant scientific literature and the necessary considerations for implementation.
View Article and Find Full Text PDF

Background: The practice of starving patients in the immediate period after upper gastrointestinal surgery is widespread. Early oral intake has been shown to be feasible and may result in faster recovery and decrease length of hospital.

Aim: To evaluate the feasibility and safety of oral nutrition on postoperative early feeding after upper gastrointestinal surgeries.

View Article and Find Full Text PDF

Objective: To evaluate the intra- and inter-reliability and the ease of measuring the quadriceps muscle thickness using bedside ultrasound.

Methods: This is a prospective, observational study. The assessment of quadriceps muscle thickness was performed at two reference points and was quantified using portable B-mode ultrasound in two healthy volunteers.

View Article and Find Full Text PDF
Article Synopsis
  • The Brazilian medical organizations AMIB and SBPT are revamping guidelines for mechanical ventilation, recognizing its impact on patient survival in intensive care units.
  • Experts were assigned to research and write about 29 key topics in mechanical ventilation, culminating in a collaborative review process.
  • The final recommendations were discussed and approved during a forum held in São Paulo in August 2013 with contributions from numerous specialists in the field.
View Article and Find Full Text PDF

Perspectives on invasive and noninvasive ventilatory support for critically ill patients are evolving, as much evidence indicates that ventilation may have positive effects on patient survival and the quality of the care provided in intensive care units in Brazil. For those reasons, the Brazilian Association of Intensive Care Medicine (Associação de Medicina Intensiva Brasileira - AMIB) and the Brazilian Thoracic Society (Sociedade Brasileira de Pneumonia e Tisiologia - SBPT), represented by the Mechanical Ventilation Committee and the Commission of Intensive Therapy, respectively, decided to review the literature and draft recommendations for mechanical ventilation with the goal of creating a document for bedside guidance as to the best practices on mechanical ventilation available to their members. The document was based on the available evidence regarding 29 subtopics selected as the most relevant for the subject of interest.

View Article and Find Full Text PDF

Context And Objective: Anemia and blood transfusions are common in intensive care. This study aimed to evaluate epidemiology and outcomes among critically ill patients under a restrictive transfusion strategy.

Design And Setting: Prospective observational cohort study in an intensive care unit (ICU) at a tertiary hospital.

View Article and Find Full Text PDF

Objective: Patients undergo to cardiac surgery have more probability to develop thrombocytopenia. The heparin induced thrombocytopenia happens in 5% of the patients. The aim from this study was to evaluate the clinical importance from the severe thrombocytopenia in postoperative cardiac surgical patients.

View Article and Find Full Text PDF

Pleural tuberculosis occurs in 30% of patients with tuberculosis, and the percentage of patients with tuberculosis pleural effusions is comparable to human immunodeficiency virus HIV-positive and HIV-negative individuals, although pleural tuberculosis is rare in HIV-positive patients with CD4+ counts < 200 cells/mm(3). Pleural tuberculosis in HIV-positive patients is likely to happen in young patients, and is more frequent in intravenous drug abusers, with more acid-fast bacilli identifiable in pleural tissue. We report a rare case of pleural tuberculosis in a severely immunosuppressed HIV-positive patient, presented as two parasternum pleural-cutaneous fistula.

View Article and Find Full Text PDF

Spontaneous intracerebral hemorrhage (SICH) still presents a great heterogeneity in its clinical evaluation, demonstrating differences in the enrollment criteria used for the study of intracerebral hemorrhage (ICH) treatment. The aim of the current study was to assess the ICH Score, a simple and reliable scale, determining the 30-day mortality and the one-year functional outcome. Consecutive patients admitted with acute SICH were prospectively included in the study.

View Article and Find Full Text PDF

Unlabelled: Currently, aging of the population is a widespread global phenomenon. Therefore, the assessment of prognosis in elderly patients is needed. This study aims to identify risk factors in a population of elderly patients admitted in the intensive care unit

Methods: A prospective study in the intensive care unit of a general tertiary hospital was carried out for five months.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to assess the clinical outcomes of patients who required intra-operative blood transfusions by examining tissue perfusion markers.
  • A total of 61 adult patients undergoing surgery were evaluated, revealing that Scv02 was the most effective tissue perfusion marker for predicting mortality, with a cut-off point of 80%.
  • Findings indicated that patients with Scv02 levels at or below 80% experienced significantly lower mortality rates and fewer postoperative complications compared to those with higher Scv02 levels, suggesting that adequate perfusion is crucial for better clinical outcomes following blood transfusions.
View Article and Find Full Text PDF