Publications by authors named "Diogo Guarnieri Panazzolo"

Background: It is known that consuming a high-fat meal (HFM) induces microvascular dysfunction (MD) in eutrophic women and aggravates it in those with obesity. Our purpose was to investigate if the MD observed after a single HFM intake is caused by endothelial damage or increased inflammatory state, both determined by blood biomarkers.

Methods: Nineteen women with obesity (BMI 30-34.

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Article Synopsis
  • Ingestion of high-fat meals can lead to endothelial dysfunction (ED), an early indicator of atherosclerosis, and this study used nailfold videocapillaroscopy (NVC) to examine its effects on microvascular reactivity in lean women versus those with obesity.
  • The study involved women aged 19-40, who were divided into control and obesity groups, and their blood was analyzed for various lipid and glucose levels before and after consuming a high-fat meal.
  • Results showed that the obesity group had significant differences in microvascular reactivity and lipid profiles compared to the control group, indicating that high-fat diets could negatively impact endothelial function in women with obesity.
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Introduction: In this report, we describe challenges we encountered in the clinical management of a patient with hypoparathyroidism who had previously undergone a bariatric procedure.

Case Presentation: We report the case of a 38-year-old Caucasian woman who had undergone a Roux-en-Y gastric bypass procedure for treatment of obesity. She also had a past history of right lobectomy to treat a benign thyroid nodule.

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Objectives: Estrogen has been shown to play an important protective role in non-reproductive systems, such as the cardiovascular system. Our aim was to observe gender differences in vivo with regard to the increase in macromolecular permeability and leukocyte-endothelium interaction induced by ischemia/reperfusion as well as in microvascular reactivity to vasoactive substances using the hamster cheek pouch preparation.

Methods: Thirty-six male and 36 female hamsters, 21 weeks old, were selected for this study, and their cheek pouches were prepared for intravital microscopy.

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