Teicoplanin versus vancomycin for proven or suspected infection.

Background: Vancomycin and teicoplanin are commonly used to treat gram-positive infections, particularly those caused by methicillin-resistant Staphylococcus aureus (MRSA). There is uncertainty regarding the effects of teicoplanin compared to vancomycin on kidney function with some previous studies suggesting teicoplanin is less nephrotoxic than vancomycin.

Objectives: To investigate the efficacy and safety of vancomycin versus teicoplanin in patients with proven or suspected infection.