Publications by authors named "Dino Sepulveda"

Article Synopsis
  • * Researchers collected fecal samples from 775 hospitalized patients and 357 community members; they found high rates of fluoroquinolone-resistant (FQR), extended-spectrum cephalosporin-resistant (ESCR), and multidrug-resistant (MDR) GNB in both groups.
  • * The study highlighted that antibiotic-resistant bacteria are common in both hospitals and communities, emphasizing the need for further investigation into how these resistant strains spread between these environments.
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Health systems do not have the capacity to finance all services. The impact of choosing one option or another is important in order to prioritize health resources. Citizen participation can help to set priorities or to select the interventions that will receive public funding.

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Objective: To develop a reporting guideline for overviews of reviews of healthcare interventions.

Design: Development of the preferred reporting items for overviews of reviews (PRIOR) statement.

Participants: Core team (seven individuals) led day-to-day operations, and an expert advisory group (three individuals) provided methodological advice.

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Objectives: Guideline panels must assess the magnitude of health benefits and harms to develop sensible recommendations. However, they rarely use explicit thresholds. In this paper we report on the piloting and the use thresholds for benefits and harms.

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Since the end of the Cold War, health has gone from a peripheral concern in foreign policy negotiations to a prominent place on the global political agenda. While the rise of health onto the foreign policy agenda is by now old news, the driving forces behind its expansion into new political spheres remain understudied and undertheorized. This article builds on empirical findings from a four-country study of the integration of health into foreign policy, and proposes a conceptual approach to GHD to improve understanding of the conditions under which health is successfully positioned on the foreign policy agenda.

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Sarocladium kiliense is a saprophyte fungus that can cause opportunistic infections associated to invasive procedures. We report a multi-hospital nosocomial outbreak of fungemias due to this agent. Patients with positive blood culture to this agent were studied after six bloodstream infections identified in three Chilean hospitals in July 2013 were reported to Ministry of Health National Infection and Prevention Control Program.

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Background: Global health diplomacy (GHD) has become an important field of investigation due to health concerns increasingly entering the foreign policy domain. Much of the existing academic writing focuses on North-South cooperation in global health, and emphasizes the role of security and economic interests by Northern countries as drivers of GHD. Chile presents a favourable environment for an expanded involvement in future GHD activities.

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The Ministry of Health of Chile, aiming to improve the quality of clinical practice guidelines, gradually incorporated the GRADE system (Grading of Recommendations, Assessment, Development and Evaluation) to develop evidence based recommendations. This system summarizes and evaluates the certainty of the available evidence. It moves from evidence to decision in a systematic and transparent manner, based on four main dimensions: balance between benefits and harms, certainty of evidence, patient's values and preferences and use of resources.

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