Methodology for evaluation of complex school-based health promotion interventions.

There is a need for careful examination of large volumes of collected (structured and unstructured) information related to school-based evaluation. There is also no published, comprehensive framework/s for evaluating complex interventions in Irish primary schools. The aim of this paper is to outline a methodology for process evaluation of an Irish primary school-based physical activity (PA) and nutrition intervention.

Do research collaborations age like wine? Absolute and relative measures of CANZUK research partnerships' strength since the 1950s.

Although previous studies of today's globalised and competitive research landscape have mentioned the research collaborations of CANZUK countries (i.e., Australia, Canada, New Zealand, and the United Kingdom), none have yet studied them in detail.

Closed Shop or Collaborative Hub? An Analysis of the Partners' Importance in CANZUK Countries' Research Collaborations.

Collaborative partners are important in international research collaboration. The research collaborations between four CANZUK countries (Canada, Australia, New Zealand and the United Kingdom) are examined to see whether their research connections are different from the research relationships with other countries. This paper measures the affinity index values and analyses the development of research collaborations among CANZUK countries with those between the CANZUK and other countries.

Dismantling weight stigma: A group intervention in a partial hospitalization and intensive outpatient eating disorder treatment program.

The authors piloted a weight stigma psychotherapy group at an eating disorder partial hospitalization (PHP) and intensive outpatient program (IOP). This was an optional, transdiagnostic eating disorder group for patients with past/present weight stigma experiences related to being in large bodies. A total of 36 individuals participated in the weekly group from June 2018 to June 2019 during their PHP/IOP episode of care.

'A Healthy CIT': An Investigation into Student Health Metrics, Lifestyle Behaviours and the Predictors of Positive Mental Health in an Irish Higher Education Setting.

Higher Education Institutions (HEIs) are potent health promotion settings, uniquely positioned to aid societal efforts to combat non-communicable diseases (NCDs). International evidence suggests that health metrics and lifestyle behaviours of higher education students are sub-optimal, yet a dearth of contemporary Irish data exists. This study aimed to examine sex differences in student lifestyle behaviours and identify significant predictors of positive mental health in an Irish HEI setting.

Continual expression of Rab5(Q79L) causes a ligand-independent EGFR internalization and diminishes EGFR activity.

The amount of cell-surface Epidermal Growth Factor Receptor (EGFR) available to secreted ligand (EGF) dictates a cell's ability to mediate cell proliferation, differentiation or migration. Multiple factors regulate EGFR cell-surface expression including the rates of protein synthesis and protein degradation, and the endocytic trafficking of both stimulated and unstimulated EGFR. Rab5 is a 25 kDa protein that is localized to the plasma membrane and the early endosome.

Expression of dominant negative rab5 in HeLa cells regulates endocytic trafficking distal from the plasma membrane.

Ligand-mediated endocytosis is an important regulatory mechanism of epidermal growth factor (EGF) receptor (EGFR) signal transduction. Coordinated EGFR internalization and degradation function to regulate the spatial and temporal components of EGFR-effector interactions. In an effort to better understand the molecular mechanisms that control these events, we examined the role of rab5 in the endocytic trafficking of the EGFR.

Stability and movement of a one-link neuromusculoskeletal sagittal arm.

This paper's focus is the stability, point-to-point, and rhythmic movements of a one-link sagittal arm. The system is highly nonlinear in all its physical and physiological attributes. The major physiological characteristics of this system are simultaneous activation of a pair of nonlinear muscle-like actuators for control purposes, existence of nonlinear spindle-like sensors, and actions of gravity and loading.