Publications by authors named "Dingzhang Chen"

Article Synopsis
  • - A case of an infant with obstetric brachial plexus injury was diagnosed at 2 years old after showing limited movement in her right arm, which followed a clavicular fracture caused by shoulder dystocia.
  • - High-frequency ultrasound revealed that the C6 nerve root was thinner on the injured side, indicating possible nerve damage, and a traumatic neuroma was detected at the upper trunk.
  • - Surgical findings confirmed the ultrasound diagnosis, and postoperative pathology indicated the presence of a brachial plexus traumatic neuroma, validating the imaging results.
View Article and Find Full Text PDF

Background: Thoracic outlet syndrome (TOS) with the lower trunk compression of brachial plexus (BP) is difficult to diagnosis. This study aimed to summarize the features of thoracic outlet syndrome (TOS) with the lower trunk compression of brachial plexus observed on high-frequency ultrasonography (HFUS).

Methods: The ultrasound data of 27 patients who had TOS with the lower trunk compression of brachial plexus were collected and eventually confirmed by surgery.

View Article and Find Full Text PDF

Melanotic nerve sheath tumor (MNST) is a rare variant of schwannoma. Here, we report an unusual case of multiple MNST lesions located in the upper limb nerves. The patient presented with a mass on the left wrist in 2016 and another mass on the left thumb in 2017.

View Article and Find Full Text PDF

Background: Cervical plexus (CP) tumours are difficult to diagnose because of atypical symptoms. This study aimed to summarize the features of a normal CP and CP tumours observed on high-frequency ultrasonography.

Methods: The ultrasound data of 11 CP tumour patients and 22 normal volunteers were collected.

View Article and Find Full Text PDF

Background: Computer-aided diagnosis (CAD) systems are being applied to the ultrasonographic diagnosis of malignant thyroid nodules, but it remains controversial whether the systems add any accuracy for radiologists.

Objective: To determine the accuracy of CAD systems in diagnosing malignant thyroid nodules.

Methods: PubMed, EMBASE, and the Cochrane Library were searched for studies on the diagnostic performance of CAD systems.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate the effectiveness of high-resolution ultrasonography in diagnosing brachial plexus root lesions among 37 patients.
  • Results showed that ultrasonography successfully identified most C5-7 nerve roots and correctly diagnosed various root injuries and tumors in the majority of cases.
  • Though generally accurate, the method missed 2 T1 nerve root avulsions; it still proved to be a valuable tool for quick diagnosis and localization of brachial plexus root lesions.
View Article and Find Full Text PDF

Purpose: To evaluate the feasibility and accuracy of high-frequency sonography (US) in diagnosing traumatic brachial plexus (BP) lesions and neoplasms in the adult.

Methods: Eleven patients with suspected BP closed trauma, 6 patients with BP neoplasm, and 12 healthy volunteers were scanned. The US findings were compared with surgical findings.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigated the effects of high-intensity focused ultrasound (HIFU) ablation on the hearts of dogs, focusing on its immediate biological response and feasibility for myocardial tissue ablation.
  • Six dogs underwent HIFU treatment with varying energy levels, while both in vivo and in vitro tests were conducted to assess lesion sizes and focal temperatures.
  • Results showed that HIFU effectively created controlled lesions in the heart, leading to increased cardiac markers and decreased local heart motion without significantly impacting the overall heart function.
View Article and Find Full Text PDF

The goal of this study was to prospectively investigate the feasibility of preoperative ultrasonography evaluation in the differentiation between pre- and postganglionic traumatic brachial plexus lesions. Two expert radiologists employed ultrasonography to observe the morphology of the brachial plexus in 23 patients with suspected traumatic brachial plexus lesions and 40 healthy volunteers. The detection rate was 100% (126/126) for the C5 through C7 nerve roots and upper and middle trunks and three fascicles, 84% (106/126) for the C8 roots and the lower trunks and 64% (81/126) for T1 roots in all subjects.

View Article and Find Full Text PDF

Objective: To investigate the mechanism of rosiglitazone (RSG, the activator of peroxisome proliferators activated receptor lambda) for inhibiting endothelin-1 (ET-1)-induced neonatal rat cardiac myocyte hypertrophy and the role of protein kinase C (PKC) and c-fos.

Methods: In vitro cultured neonatal rat cardiac myocytes were treated with ET-1, phorbol ester (PMA, the PKC activator), ET-1+RSG, ET-1+chelerythrine (che, the PKC inhibitor), PMA+RSG, or without treatment (control), respectively. The effects of RSG on the protein content, (3)H-leucine incorporation, PKC activity and C-fos protein expression were observed in the cardiac myocytes stimulated with ET-1 or PMA.

View Article and Find Full Text PDF

Objective: To compare the prognostic value of regional longitudinal ventricular systolic velocities with that of maximal oxygen consumption (VO(2max)) in patients with dilated cardiomyopathy (DCM).

Methods: VO(2max) derived from cardiopulmonary exercise tests and regional longitudinal ventricular systolic velocities obtained from tissue Doppler imaging were compared in 18 DCM patients with cardiac events (death, cardiac transplantation, hospitalization, group A) and 24 patients without cardiac events (group B). Peak velocities during isovolumic contraction (is) and ejection (ez) were interrogated at the mitral or tricuspid annulus (site 1), at the mid parts of the walls (site 3, at the level of papillary muscle), and at the midpoints (site 2) between sites 1 and 3 of interventricular septum (S), lateral wall of LV (L) and of RV (R) in apical 4 chambers view.

View Article and Find Full Text PDF

Objective: To observe the relationship between protein sythesis and cardiomyocyte viability in neonatal rats.

Methods: The protein sythesis in neonatal rat cardiomyocytes was measured according to Brandford's method, the absorbance at 490 nm (A(490 nm)) of the cells was measured with MTT assay and the cell viability evaluated by the ratio of A(490 nm) to the total cell number.

Results: ET-1 increased cardiomyocyte protein synthesis dose-dependently, and this effect was attenuated by the application of lacidipine and tetramethylpyrazines Higher doses of ET-1 resulted in lower A(490 nm)/total cell number ratio, which was further lowered by larcidipine and tetramethylpyrazine.

View Article and Find Full Text PDF

Objective: To evaluate the effect of high altitude on uterine and umbilical artery blood flow dynamics during normal pregnancy.

Method: Uterine artery blood flow parameters of the pregnant (34) and nonpregnant (37) subjects and umbilical artery blood flow parameters of 119 subjects living at high altitude or at low altitude were measured with color Doppler flow imaging system.

Results: Uterine artery diameter, blood flow volume increased during pregnancy at both altitude, and uterine artery blood flow volume and diameter were smaller at high altitude than at low altitude [(0.

View Article and Find Full Text PDF

Synopsis of recent research by authors named "Dingzhang Chen"

  • - Recent research by Dingzhang Chen primarily focuses on the application of high-frequency ultrasonography (HFUS) for diagnosing various conditions related to the brachial plexus, including obstetric injuries, thoracic outlet syndrome, and tumors, providing detailed insights into ultrasound characteristics and improving diagnostic accuracy.
  • - Chen's work highlights the use of HFUS as a non-invasive diagnostic tool in pediatric and adult populations, demonstrating its effectiveness in identifying complex conditions that may have atypical presentations, thereby facilitating timely surgical intervention.
  • - Additionally, his studies include systematic reviews on computer-aided diagnosis systems for malignant thyroid nodules, reinforcing the importance of innovative diagnostic technologies and methods in enhancing the precision of medical imaging and evaluation.