Regulation of the β‑catenin/LEF‑1 pathway by the siRNA knockdown of RUVBL1 expression inhibits breast cancer cell proliferation, migration and invasion.

RUVBL1 is a protein characterized by its DNA‑dependent ATPase activity and DNA deconjugating enzyme function. It is a member of the ATPase (AAA+) protein family associated with various cellular processes. Available research confirms that the expression of RUVBL1 is upregulated in breast cancer (BRCA) cell lines; however, the mechanisms underlying its functional role in BRCA remain unclear.

Phase Behavior of Polyglycerol Ester-Based Nanoemulsions.

Nanoemulsions were prepared using polyglycerol esters as emulsifiers. The effects of emulsifiers, oils, and polyols on the phase behavior of nanoemulsions were analyzed by phase diagram method using caprylic acid capric triglyceride (318), mineral oil, and squalane (Squ) as oils respectively. Various factors affecting the area of the oil-in-water (O/W) nanoemulsion were investigated.