CT-CBCT deformable registration using weakly-supervised artifact-suppression transfer learning network.

Computed tomography-cone-beam computed tomography (CT-CBCT) deformable registration has great potential in adaptive radiotherapy. It plays an important role in tumor tracking, secondary planning, accurate irradiation, and the protection of at-risk organs. Neural networks have been improving CT-CBCT deformable registration, and almost all registration algorithms based on neural networks rely on the gray values of both CT and CBCT.