Icariin promotes bone marrow mesenchymal stem cells osteogenic differentiation via the mTOR/autophagy pathway to improve ketogenic diet-associated osteoporosis.

Background: Icariin, a traditional Chinese medicine, has demonstrated anti-osteoporotic properties in ovariectomized mice. However, its effectiveness in preventing bone loss induced by ketogenic diet (KD), which mimics osteoporosis in human, remains unexplored. This study aims to investigate icariin's impact on KD-induced bone loss in mice.

Real-Time Detection of Concealed Threats with Passive Millimeter Wave and Visible Images via Deep Neural Networks.

Passive millimeter wave has been employed in security inspection owing to a good penetrability to clothing and harmlessness. However, the passive millimeter wave images (PMMWIs) suffer from low resolution and inherent noise. The published methods have rarely improved the quality of images for PMMWI and performed the detection only based on PMMWI with bounding box, which cause a high rate of false alarm.

Differential expression of miR-4492 and IL-10 is involved in chronic rhinosinusitis with nasal polyps.

Chronic rhinosinusitis (CRS) is one of the most common types of respiratory disease and affects a large proportion of the population worldwide. The clinical differences between CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP) facilitate studies on the development of polyps. In the present study, next-generation sequencing was performed to identify differentially expressed microRNAs (miRNAs/miRs) in CRSwNP vs.