Foliar uptake screening: A promising strategy for identifying wheat varieties with low lead accumulation.

Lead (Pb) contamination in wheat grain is of great concern, especially in North China. Atmospheric deposition is a major contributor to Pb accumulation in wheat grain. Screening low Pb accumulating wheat varieties has been an effective method for addressing Pb contamination in wheat grain.

Effects of meteorological factors and groundwater depths on sap flow density of in a desert oasis, Taklamakan Desert, China.

Accurate estimation of desert vegetation transpiration is key to regulating desert water resources of desert ecosystems. Sap flow density (SFD) can indirectly reflect a tree's transpiration consumption, and it has been affected by climate warming and groundwater depths in desert ecosystems. Sap flow responses to meteorological conditions and groundwater depths are further affected by tree of different sizes.

Nitric oxide-induced endoplasmic reticulum stress of Schistosoma japonicum inhibits the worm development in rats.

Schistosomiasis, caused by Schistosoma spp., is a zoonotic parasitic disease affecting human health. Rattus norvegicus (rats) are a non-permissive host of Schistosoma, in which the worms cannot mature and cause typical egg granuloma.

Schistosome egg-derived extracellular vesicles deliver Sja-miR-71a inhibits host macrophage and neutrophil extracellular traps via targeting Sema4D.

Background: Macrophages and neutrophils are rapidly recruited around Schistosome eggs to form granulomas. Extracellular traps (ETs) of macrophages and neutrophils are part of the pathogen clearance armamentarium of leukocytes. Schistosome eggs possess the ability to resist attack by the host's immune cells and survive by employing various immune evasion mechanisms, including the release of extracellular vesicles (EVs).

Metagenomic Analysis Reveals Variations in Gut Microbiomes of the -Transmitting Snails and .

snails play a crucial role in the transmission of the human blood fluke . The gut microbiota of intermediate hosts is known to influence their physiological functions, but little is known about its composition and role in snails. To gain insights into the biological characteristics of these freshwater intermediate hosts, we conducted metagenomic sequencing on and to investigate variations in their gut microbiota.

Knockout of Sema4D alleviates liver fibrosis by suppressing AOX1 expression.

Liver fibrosis can occur in many chronic liver diseases, and no effective treatments are available due to the poorly characterized molecular pathogenesis. Semaphorin 4D (Sema4D) has immune functions and serves important roles in T cell priming. Here, we found that Sema4D was highly expressed in fibrotic liver, and the expression of Sema4D increased with hepatic stellate cells (HSCs) activation.

CEBPα/miR-101b-3p promotes meningoencephalitis in mice infected with Angiostrongylus cantonensis by promoting microglial pyroptosis.

Background: Angiostrongylus cantonensis (A. cantonensis) infection can induce acute inflammation, which causes meningoencephalitis and tissue mechanical injury to the brain. Parasite infection-induced microRNAs play important roles in anti-parasite immunity in non-permissive hosts.

A 3D printable, highly stretchable, self-healing hydrogel-based sensor based on polyvinyl alcohol/sodium tetraborate/sodium alginate for human motion monitoring.

Self-healing hydrogels have great application potential in the field of bio-sensors due to their self-healing, flexibility and excellent tensile properties. However, most hydrogel-based sensors are processed by template method, which is unable to fabricate complex three-dimensional (3D) structures, and limits the development of hydrogel-based sensor devices. A simple yet efficient one-pot method was proposed to fabricate polyvinyl alcohol/sodium tetraborate/sodium alginate hydrogel inks (SPB), also a fabricating process of self-healing hydrogel based on 3D printing technology has been proposed.