Risk factors for death in children with severe hand, foot, and mouth disease in Hunan, China.

Background: In recent years, outbreaks of hand, foot, and mouth disease (HFMD) have increased throughout East and Southeast Asia, especially in mainland China. The disease now presents as an increasingly serious public health threat in China.

Methods: A case-control study was designed to examine risk factors associated with death from severe HFMD.

[The dose-response relationship of chrysotile asbestos exposure and lung cancer in cohort study].

Objective: To clarify the dose-response relationship between asbestos dust exposure and lung cancer incidence in chrysotile asbestos miners by fixed cohort study and to investigate the incidence rates of lung cancer in exposure to different concentrations of asbestos dust.

Methods: A retrospective cohort study was conducted in 1932 asbestos miners who registered from January 1, 1981 to December 31, 1988, had worked for at least 1 year, and had no obvious cardiopulmonary diseases; the cohort study began in July 2009 and covered a time span of 29 years (1981 - 2009). The personal information, occupational history, disease history, and health data of these miners were recorded, and the monitoring data on dust concentrations in the mine over the years were collected.

[Effect of magnitude and duration on the performance of Cumulative Sum].

To explore the effect of magnitude and duration on the performance of Cumulative Sum (CUSUM), with simulation method used on the subject after the insertion of 11 outbreak events into baseline data with Poisson distribution. Sensitivity fluctuated from 9.1% to 100.

[Characteristics and stability of surveillance data on respiratory syndrome, during the Shanghai World Expo in Pudong New District].

Objective: To reveal the characteristics and stability of the system through the analyzing the surveillance data of respiratory-feverous syndrome via the syndromic surveillance system which was established during the Shanghai World Expo in Pudong New District and provide references for the development and operation optimization on this Mass Gatherings Surveillance Systems.

Methods: Data used was from the surveillance data of respiratory-feverous syndrome collected from Pudong New District Syndromic Surveillance System, through May 1 to October 31, 2010. On the basis of description of data characteristics, correlation analyses were conducted, when compared to the surveillance data of respiratory-feverous syndrome and Pudong influenza-like illness (ILI) used as reference.

Epidemic features affecting the performance of outbreak detection algorithms.

Background: Outbreak detection algorithms play an important role in effective automated surveillance. Although many algorithms have been designed to improve the performance of outbreak detection, few published studies have examined how epidemic features of infectious disease impact on the detection performance of algorithms. This study compared the performance of three outbreak detection algorithms stratified by epidemic features of infectious disease and examined the relationship between epidemic features and performance of outbreak detection algorithms.

[Nested case-control study of chrysotile and lung cancer].

Objective: To investigate the relationship between simple exposure to chrysotile and lung cancer.

Methods: The nested case-control study method was used. All of lung cancer cases collected from a male fixed prospective cohort with follow-up of 30 years served as cases and a 1:4 matched proportion was used to select non-cancer case as controls.

[Paired-control study on the effect of vanadium on neurobehavioral functions].

Objective: To investigate the change of neurobehavioral functions of workers with long term exposure to vanadium.

Methods: A total of 106 workers with exposure to vanadium were paired with workers without exposure to vanadium. The WHO-NCTB was employed to assess the neurobehavioral functions.

[Behavioral features of men who have sex with men].

Objective: This behavioral surveillance survey in Sichuan province was aimed to gain an insight into the behavioral features related to HIV prevalence among men who have sex with men (MSM).

Methods: The pilot survey was initiated in the year from September to December, 2003. Two cities, Chengdu and Nanchong, were selected as the surveillance sites.