Mandibuloacral dysplasia type A-associated progeria caused by homozygous LMNA mutation in a family from Southern China.

Background: Mandibuloacral dysplasia type A (MADA) is a rare autosomal recessive disorder, characterized by growth retardation, skeletal abnormality with progressive osteolysis of the distal phalanges and clavicles, craniofacial anomalies with mandibular hypoplasia, lipodystrophy and mottled cutaneous pigmentation. Some patients may show progeroid features. MADA with partial lipodystrophy, more marked acral, can be caused by homozygous or compound heterozygous mutation in the gene encoding lamin A and lamin C (LMNA).

Erythema associated with pain and warmth on face and ears: a variant of erythermalgia or red ear syndrome?

Erythermalgia is a rare cutaneous disorder characterized by attacking of erythema, pain and increased temperature, which primarily involves the extremities and may infrequently extend to the neck, face, ears and even the scrotum. We reported an 18-year-old woman who presented with 3 years history of sole involvement of attacking erythema, pain and warmth over her face and ears without any other associations. The frequency and severity of the flares progressed gradually during the course.

Cutaneous pili migrans: a case report and review of the literature.

Background: Cutaneous pili migrans is a rare condition in which the hair shaft penetrates the superficial layer of the skin and produces a creeping eruption mimicking the lesion of cutaneous larva migrans.

Methods: We report a 28-year-old Chinese man who presented with a painful and slow-moving black, linear eruption on the left sole after walking on a waterlogged street wearing slippers without socks.

Results: The lesion started at the anterior part of the foot near the external border, extending linearly along Langer's line towards the lateral side.