Publications by authors named "Ding-Yan Zhao"
Objective: To investigate the effect of Polyetheretherketone (PEEK) rod semi-rigid pedicle screw fixation system in lumbar spine non-fusion surgery.
Methods: A total of 74 patients with tow-level lumbar degenerative diseases who underwent surgery from March 2017 to December 2019 were divided into PEEK rod group and titanium rod group. In the PEEK rod group, there were 34 patients, including 13 males and 21 females, aged from 51 to 79 years old with an average of (62.
Objective: To provide the cobweb classification system (CCS) for the precise digital location and description of the neurological compression in cervical degenerative disease (CDD), and the reliability and the clinical subgroup analysis of the system were tested and analyzed.
Methods: The CCS consisted of three parts: compression zones (-), degrees (, ) and ossification (, , ). Computerized tomography (CT) and magnetic resonance imaging (MRI) images from 238 CDD patients were reviewed.
Aims: Whether to perform hybrid surgery (HS) in contrast to anterior cervical discectomy and fusion (ACDF) when treating patients with multilevel cervical disc degeneration remains a controversial subject. To resolve this we have undertaken a meta-analysis comparing the outcomes from HS with ACDF in this condition.
Methods: Seven databases were searched for studies of HS and ACDF from inception of the study to 1 September 2019.
Article Synopsis
- Zhao-he and Sun-qingling are both recognized as co-first authors of the manuscript.
- The original article did not clearly communicate this important authorship information.
- The oversight was due to the negligence and mistakes of the authors involved.
Objective: To observe the early clinical effect of perfusion bone cement screw for lumbar degenerative diseases with osteoporosis.
Methods: The clinical data of 28 patients with lumbar degenerative diseases combined with moderate to severe osteoporosis treated by posterior lateral graft fusion with perfusion of bone cement screws from June 2015 to June 2017 were retrospectively analyzed. There were 9 males and 19 females, aged from 55 to 86 years old with an average of 76 years.
Although the Mobi-C artificial disc and the ROI-C cervical cage have been widely used in the treatment of cervical degenerative disc diseases (CDDD), few reports addressed the features of combined application of both devices. This study is aimed at comparing the clinical and radiological outcomes of treating contiguous two-level CDDD using Mobi-C and ROI-C combined in a hybrid surgery (HS) with anterior cervical discectomy and fusion (ACDF) using ROI-C. We reviewed ninety-one patients who underwent HS (n = 48) or ACDF (n = 43) surgery for symptomatic contiguous two-level CDDD.
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- The study examines the effectiveness of self-locking stand-alone cages for cervical fusion and identifies different fusion states at the index level among 42 patients over a 5-year follow-up period.
- The overall fusion rate was high at 97.4%, with type IV showing the highest fusion proportion, and all types demonstrated significant improvement in clinical outcomes.
- The research highlights the dynamic nature of the fusion process and suggests that factors like cage location and cervical spine alignment may influence the fusion state, but all types resulted in satisfactory clinical results.
Article Synopsis
- The study investigates the safety and effectiveness of cell transplantation for spinal cord injury (SCI) patients, a topic that has been debated for nearly 40 years.
- Analysis of 21 controlled studies involving 973 patients showed significant improvements in various scores and measures after cell transplantation, particularly with stem cells and treatment administered later than 14 days post-injury.
- The study concludes that cell transplantation is generally safe and can lead to significant benefits for SCI patients, especially when using specific dosages and methods like intrathecal injection.
The Editor-in-Chief has retracted this article [1] because of an error in the meta analysis. Re-examination of the data has showed that there is only one published randomized controlled trial comparing Superion with XStop. Due to a misunderstanding of the published clinical data, the conclusions drawn in the article are incorrect.
View Article and Find Full Text PDF: Peripheral nerve injury (PNI) has devastating consequences. Dorsal root ganglion as a pivotal locus participates in the process of neuropathic pain and nerve regeneration. In recent years, gene sequencing technology has seen rapid rise in the biomedicine field.
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- The study aims to compare complications between two common surgeries for cervical degenerative disc disease: anterior cervical discectomy and fusion (ACDF) and anterior cervical disc replacement (ACDR).
- A systematic review and meta-analysis will be conducted using various medical databases to collect and analyze relevant studies, assessing data quality and outcomes.
- Findings will be presented at conferences and published in peer-reviewed journals, offering important guidance for spine surgeons and device designers.
Article Synopsis
- Anterior cervical artificial disc replacement (ACDR) shows promise for treating single-level cervical spondylosis, but its effectiveness for two contiguous levels is still debated compared to anterior cervical decompression and fusion (ACDF).
- A systematic review and meta-analysis were conducted, reviewing literature up to July 2017, focusing on various patient outcome measures like neck disability index and overall clinical success among 2715 patients from multiple studies.
- Results demonstrated that ACDR outperformed ACDF in several metrics, including neck disability and patient satisfaction, indicating it may be a better option for treating two levels of cervical spondylosis.
Background: Decompressive laminectomy (DI) is a standard operation for lumbar spinal stenosis (LSS) patient with severe claudication symptoms for many years. However, patients whose symptom severity does not meet undergoing invasive surgery make therapeutic options into dilemma. Interspinous spacers (ISP) bridge the gap between surgical interventions and CC in management of LSS.
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