Publications by authors named "Ding-Hai Luo"
Article Synopsis
- Endoscopy is crucial for detecting esophageal squamous cell carcinoma and precancerous lesions, but improving detection rates is still a challenge.
- A new system using deep convolutional neural networks (CNNs) was developed and tested to enhance the detection of high-risk esophageal lesions (HrELs) during endoscopy, and showed significant improvement in detection rates.
- In a clinical trial with over 3,100 patients, the CNN-assisted endoscopy group had a HrEL detection rate of 1.8%, compared to 0.9% in the control group, demonstrating greater sensitivity, specificity, and accuracy without any adverse events.
Purpose: Hyperuricemia and metabolic syndrome (MetS) have been shown to correlate with prognosis in patients with malignant tumors. The present study evaluated the relationship between preoperative hyperuricemia and MetS in colorectal cancer (CRC) patients and analyzed the effect of this combination on prognosis within 5 years.
Patients And Methods: The study enrolled patients who had undergone radical CRC resection at three independent medical centers from January 2014 to December 2016.
Objectives: Although endoscopic resection is an accepted technique for upper gastrointestinal subepithelial tumors (SETs) originating from the muscularis propria (MP) layer, published data regarding its complications are highly variable and limited to small data series. This study aimed to analyze the safety of endoscopic resection in a large case series.
Methods: A total of 726 consecutive patients with 733 upper gastrointestinal SETs originating from the MP layer underwent endoscopic resection from June 2005 to December 2014.
Changes in the expression of the Notch1 intracellular domain (NICD) and p21 proteins have been shown to be closely associated with the development and progression of a number of cancers. The present study aimed to investigate the expression levels of the two proteins in gastric carcinoma and precancerous lesions, and to determine the clinical significance of this. A total of 109 gastric cancer, 57 precancerous gastric lesion, 50 chronic superficial gastritis and 17 normal gastric mucosa patients were recruited for immunohistochemical staining of NICD and p21 protein expression.
View Article and Find Full Text PDF