A study explored the characteristics and outcomes of childhood acute lymphoblastic leukemia (ALL) cases with specific gene mutations, involving 14 patients over 7 years.
The majority of affected children were girls, with a median age of just over 4 years, and they exhibited a high rate of complete remission (79%) after initial treatment but a notable recurrence rate of 21%.
Despite challenges, many children achieved long-term survival, and the overall 5-year survival rate for the group was an encouraging 92%.