To investigate the application of low temperature plasma ablation combined with fullly degradable sinus stent system in the treatment of congenital choanal atresia mainly menbranous atresia. A child with membranous bilateral choanal atresia admitted in April 2023 was analyzed. This case underwent endoscopic ablative posterior nostriplasty and placed a fully degradable drug stent in bilateral operative cavities.
View Article and Find Full Text PDFRevealing the effect of surface structure changes on the electrocatalytic performance is beneficial to the development of highly efficient catalysts. However, precise regulation of the catalyst surface at the atomic level remains challenging. Here, we present a continuous strain regulation of palladium (Pd) on gold (Au) via a mechanically controllable surface strain (MCSS) setup.
View Article and Find Full Text PDFBackground: Long-term ozone (O) exposure has been associated with cardiovascular disease (CVD) mortality in mounting cohort evidence, yet its relationship with incident CVD was poorly understood, especially in low- and middle-income countries (LMICs) experiencing high ambient air pollution.
Methods: We carried out a nationwide perspective cohort study from 2010 through 2018 by dynamically enrolling 36948 participants across Chinese mainland. Warm-season (April-September) O concentrations were estimated using satellite-based machine-learning models with national coverage.
Background: Prediabetes is associated with an increased risk of cardiovascular diseases and all-cause mortality. Rare research in China has evaluated the prevalence of prediabetes among children and adolescents using the HbA1c criterion or the combined FPG-or-HbA1c diagnostic criterion, and researchers paid no attention to the distributions of blood glucose in Shenzhen, especially for juveniles.
Methods: We conducted a school-based cross-sectional study based on the first-year students from 17 primary, middle, and high schools.
The theory of knowledge, attitude and practice (KAP) can well explain the whole process of pregnant females' practice to obtain balanced nutrition. However, the process of KAP works very differently in populations with different sociodemography. This study aims to investigate the sociodemographic determinants associated with pregnant females' nutritional KAP and find a way to locate the vulnerable pregnant females who would benefit most from intervention.
View Article and Find Full Text PDFObjective: To explore the clinical benefits of Biyuan Tongqiao granules (BTG) combined with mometasone furoate nasal spray (MFNS) on the symptoms of children with allergic rhinitis (AR).
Methods: Seventy-eight children with AR who visited the Pediatric Department of our hospital from May 2019 to May 2020 were selected and randomly divided into the BTG group (treated with BTG alone), MFNS group (treated with MFNS alone), and combined group (children with the combined use of BTG and MFNS), with 26 cases in each group. The nasal symptoms and oculonasal symptoms were evaluated and observed at baseline and 2 months after treatment.
Introduction: Paternal smoking associated with childhood overweight and obesity has been a concern, but studies have not investigated smoking exposure and smoking details. We investigated the association of exposures from paternal smoking as well as smoking details on offspring overweight/obesity.
Methods: A total of 4,513 children (aged 7-8 years) in Shenzhen were enrolled.
Cardiovascular disease (CVD) is a leading threat to global public health. Although associations between temperature and CVD hospitalization have been suggested for developed countries, limited evidence is available for developing countries or rural residents. Moreover, the effect of apparent temperature (AT) on the spectrum of cause-specific CVDs remains unknown.
View Article and Find Full Text PDFExisting PM-morbidity studies using daily mean concentration as exposure metric may fail to capture intra-day variations of PM concentrations, resulting in underestimated health impacts to some extent. This study introduced a novel indicator, daily excessive concentration hours (DECH), defined as sums of per-hourly excessive concentrations of PM against a specific threshold within a day. PM DECHs were separately calculated as daily concentration-hours >8, 10, 15, 20, and 25 μg/m (abbreviations: DECH-8, DECH-10, DECH-15, DECH-20, and DECH-25).
View Article and Find Full Text PDFBackground: Breakfast is commonly described as the most important meal of the day; however, we have little information regarding its relevance for childhood overweight and obesity in southern mainland China. This study aimed to assess the association between breakfast preferences, consumption location and overweight and obesity for children in Shenzhen.
Methods: Among 6126 children (median age 7.
Aims/introduction: Elevated concentrations of fasting plasma glucose (FPG) or hemoglobin A1c (HbA1c) are well-established independent risk factors for progression to diabetes, cardiovascular comorbidities and mortality. Most previous studies on the relationships of anthropometric measures with hyperglycemia were carried out among adults and adolescents, but few data are available for the performance predication of the predictors for diagnosing elevated FPG or HbA1c among young children.
Materials And Methods: Involving 5,556 students of aged 7-9 years, a school-based cross-sectional survey was carried out between March and June 2019 in Shenzhen, China.
Aging (Albany NY)
August 2020
Epithelial-mesenchymal transition (EMT)-related genes play an important role in immunosuppression. However, the correlations of EMT-related genes to prognosis and tumor-infiltrating lymphocytes in different cancers remain unclear. TCGA, GEO databases were used to analyze the expression, prognosis, and immune infiltration of EMT markers in cancer.
View Article and Find Full Text PDFWe aimed to explore whether there were cold and heat temperature adverse effects on years of life lost (YLL) for non-accidental mortality in Yuxi, a southwest plateau region of China. From data for 89,467 non-accidental deaths over an 8-year study period, we used a general linear regression model combined with a distributed lag non-linear model to assess the burden of disease non-accidental mortality due to ambient temperature with the YLL indicator. We estimated the mean YLL change per 1 °C decrease from the 25th to 1st percentile mean temperature as the cold effect and per 1 °C increase from the 75th to 99th percentile as the heat effect.
View Article and Find Full Text PDFGastroenterol Res Pract
January 2020
Background: Numerous studies have consistently demonstrated that high body mass index (BMI) is related to elevated serum alanine aminotransferase (ALT) among adults, but little is known about the association regarding adolescents, especially in China. In this study, we aimed to investigate the association between BMI and ALT activity among Chinese adolescents.
Methods: A school-based cross-sectional study was performed among nine high schools in Shenzhen, China between February 2017 and June 2018.
Background: Screening for elevated serum alanine aminotransferase (ALAT) can help identifying individuals at the risks of chronic and metabolic diseases, but blood collection is invasive and cannot be widely used for investigations. Considered as simple and inexpensive screening indices, individual characteristics and anthropometric measurements can be measured in a large crowd and may be important surrogate markers for ALAT levels. This study aimed to examine the diagnostic performance of individual characteristics and anthropometric parameters as predictive factors for discerning an elevated ALAT activity among Shenzhen children and adolescents.
View Article and Find Full Text PDFStatement Of Problem: The comparative efficacy of antifungal drugs on oral candidiasis remains unclear.
Purpose: The purpose of this Bayesian network meta-analysis was to investigate the efficacy of antifungal drugs on oral candidiasis.
Material And Methods: Databases, including PubMed, The Cochrane Library, and Web of Science, were accessed from the dates of their establishment to October, 2018, to collect randomized controlled trials (RCTs) of different antifungal drugs for oral candidiasis.
Background: Ambient PM has been identified as the top leading cause of risk-attributable deaths worldwide, particularly in China. Evidence suggested that PM contributed the most majority of PM concentrations in Chinese cities. However, epidemiologic knowledge to date is of wide lack regarding PM-associated health effects.
View Article and Find Full Text PDFBackground: Ambient PM (particulate matter with aerodynamic diameter ≤1 μm) is an important contribution of PM mass. However, little is known worldwide regarding the PM-associated health effects due to a wide lack of ground-based PM measurements from air monitoring stations.
Methods: We collected daily records of hospital admission for respiratory diseases and station-based measurements of air pollution and weather conditions in Shenzhen, China, 2015-2016.
Background: Research argued that daily excessive concentration hours (DECH) could be more informative through accounting for within-day variations, when assessing population-level exposure to ambient fine particle (PM). However, few studies have comparatively investigated PM-associated risks using DECH and two common metrics of daily mean and hourly peak concentration.
Methods: We collected daily records of all-cause emergency department visits (EDVs) and hourly data on air pollutants and meteorological factors from Shenzhen, China, 2015-2018.
Background: Temperature variability (TV) is closely associated with climate change, but there is no unified TV definition worldwide. Two novel composite TV indexes were developed recently by calculating the standard deviations of several days' daily maximum and minimum temperatures (TV), or hourly mean temperatures (TV).
Objectives: This study aimed to compare the mortality risks and burden associated with TV and TV using large time-series datasets collected from multiple locations in China, United Kingdom and United States.
Objective: To examine the total non-accidental mortality burden attributable to ambient temperatures and assess the effect modification of the burden by specific causes of death and individual characteristics in a high plateau area in southwest China.
Methods: Using daily mortality and meteorological data from 2009 to 2016, we applied a quasi-Poisson model combined with a distributed lag non-linear model to estimate the temperature-mortality association with the assessment of attributable fraction and number. We calculated attributable fractions and deaths with 95% empirical CIs (eCIs), that were due to cold and heat, defined as temperatures below and above the median temperature, and for mild and extreme temperatures, defined by cut-offs at the 2.
Compared with relative risk, attributable fraction (AF) is more informative when assessing the mortality burden due to some environmental exposures (e.g., ambient temperature).
View Article and Find Full Text PDFWe have successfully synthesized LaFeSiH/Bi composites by cold pressing together with vacuum annealing technology, and systematically investigated the microstructure, magnetism, mechanical performance, and magnetocaloric properties. LaFeSiH particles are well surrounded by metallic Bi, without the formation of new phase. The maximum values of the volumetric magnetic entropy change -ΔS are as high as 51, 49, and 35 mJ/cm³K around 263 K, for the composites with 5, 10 and 15 wt % Bi contents, respectively.
View Article and Find Full Text PDFThe authors analyzed the association between the standard deviation or the coefficient of variation in the glucose value, strong independent indexes for determining glycemic variability, and the prognosis of intracerebral hemorrhage. They found that glycemic variability may be associated with a poor outcome in intracerebral hemorrhage.
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