Analysis and predication of tuberculosis registration rates in Henan Province, China: an exponential smoothing model study.

Background: The World Health Organization End TB Strategy meant that compared with 2015 baseline, the reduction in pulmonary tuberculosis (PTB) incidence should be 20 and 50% in 2020 and 2025, respectively. The case number of PTB in China accounted for 9% of the global total in 2018, which ranked the second high in the world. From 2007 to 2019, 854 672 active PTB cases were registered and treated in Henan Province, China.

Characteristics of Long-term Nonprogressors and Viremia Controllers Infected with HIV-1 via Contaminated Blood Donations or Transfusions Conducted 20 Years Earlier.

To characterize long-term nonprogressors (LTNPs) and viremia controllers (VCs), infected with HIV-1 through contaminated blood donation or transfusion between 1992 and 1996 in Henan, China. LTNPs and VCs were defined by CD4+T lymphocyte (CD4) count and viral load (VL). Of 29,294 patients infected with HIV-1 via contaminated blood donation or transfusion that had conducted for more than 20 years, 92 were LTNPs/VCs.

[Risk factors associated with malnutrition of infants exposed to HIV in Henan province, 2010-2012].

Objective: To examine the malnutrition status of infants exposed to HIV in rural areas of Henan province and related risk factors.

Methods: Z scores of weight for age, height for age and weight for height of infants exposed to HIV in rural areas of Henan province born in 2010-2012 were calculated at 1, 3, 6, 9, 12 and 18 months of age. Z scores were used to evaluate the nutrition status of infants under study.

[Epidemiological survey on the hepatitis C virus and its genotyping analysis in Henan province in 2012].

Objective: To investigate the prevalence and distribution of hepatitis C virus (HCV) genotypes in Henan province in 2012.

Methods: A total of 32 203 permanent residents (1 to 74 years old) in Henan were recruited using multi-stage random samping method from March to June 2012. All participants were asked to complete a questionnaire to collect demographic information, past medical history and the exposure history of risk factors.

[Sero-prevalence and associated risk factors on hepatitis C in Maqiao township, Henan province of China].

Objective: To describe the prevalence and risk factors of hepatitis C virus (HCV) occurred in Henan province, at the end of 2011.

Methods: Five villages round Maqiao township, including 5187 residents, were selected for the study. Five-milliliter-blood was drawn from every one of the interviewee.

[Survival analysis on AIDS antiretroviral therapy in Henan province during 2003-2009].

Objective: To study the effect of a government-provided-free highly active antiretroviral treatment (HAART) program, on the reduction of mortality and relevant risk factors among adult (AIDS) patients in Henan province.

Methods: Data on the survival and deaths of AIDS patients were collected from the National HAART reporting system between 2003 and 2009. Cox proportional hazards model was applied to analyze those factors that affecting the survival time of the patients.

[Analysis on sero-conversion status of HIV-discordant spouse from 2006-2010 in Henan province].

Objective: To study the management status of HIV-discordant family in Henan province from 2006 to 2010.

Methods: Data on AIDS infected family from "AIDS Infected Family Follow-up Management and Analysis System" was collected and analyzed to understand the management status of HIV-discordant situation.

Results: The sero-conversion rates of HIV-discordant spouse were 1.

[The newly reported HIV/AIDS cases and death of HIV cases from 2008 to 2009 in Henan province].

Objective: To explore the situation and cause of new reported HIV/AIDS cases and death of HIV cases in Henan province from 2008 to 2009.

Methods: The data of HIV/AIDS cases in Henan province before the end of 2009 was downloaded from "the history card downloading site" of the national online case reporting system on Jan. 5(th), 2010.

[Study on the situation of antiretroviral therapy against HIV/AIDS in Henan province based on the CD4+ T cells count and virus load].

Objective: To analyze the CD4(+) T cells and virus load in HIV/AIDS affected population and to evaluate the HIV/AIDS antiretroviral therapy programs in Henan province.

Methods: "Henan HIV/AIDS Testing Laboratory Network Database" was used to collect the data on CD4(+) T cells and virus load (VL) value and corresponding information in HIV/AIDS population of Henan in 2009. Cross-sectional studies was used to study the constituent ratio of CD4(+) T cells and virus load value in individuals who had not received antiretroviral-treated (ART) and had joined first-line ART between the year of 2005 to 2008 among HIV/AIDS population of Henan.

[Influencing factors on the death of infants born to HIV infected mothers].

Objective: To understand the influencing factors on the death of infants born to HIV infected mothers in areas with high prevalence of HIV/AIDS in China.

Methods: Based on the follow-up cohort study targeting at HIV/AIDS infected pregnant women and their babies initiated in 2004, a survey on the death status and influencing factors on the infants born to HIV/AIDS infected mothers enrolled in this cohort from Jan.2004 to Nov.

[The change trend of mother-to-child transmission rate of HIV-1 during 2005-2007 in some areas of China].

Objective: To explore the change trend of mother-to-child-transmission (MTCT) of HIV-1 in some areas in China.

Methods: The investigation was conducted in 15 counties or districts of 4 provinces in China with relatively high HIV prevalence from January 2005 to June 2009. The data on the death and HIV-status of the babies born to HIV-positive mothers from January 2005-December 2007 in research sites were collected through 18-month following up after they were born.

[Study on the transmission of drug resistant human immunodeficiency virus-1 in Henan province].

Objective: To survey the prevalence of HIV-1 drug resistance after five years antiretroviral treatment in Henan province.

Methods: Through the cross-sectional study, serum specimens of 69 HIV infected individuals that were 2 to 25 years old who were newly diagnosed according the WHO standard from November 2007 to August 2008 and did not receive antiretroviral treatment (ART) were collected. HIV-1 pol genetic mutations associated with drug resistance were identified with RT-PCR and interpreted.