Publications by authors named "Ding Ya-Suo"

Article Synopsis
  • SCUBE1 is a protein that serves as a marker for coagulation and is linked to the prognosis of critical illnesses, specifically in patients with aneurysmal subarachnoid hemorrhage (aSAH).
  • Researchers analyzed serum SCUBE1 levels in 125 aSAH patients compared to 125 controls, finding significantly higher levels in patients along with strong correlations to established clinical scoring systems.
  • The study concludes that elevated SCUBE1 levels could be a valuable predictor of poor outcomes in aSAH patients, potentially helping to identify those at greater risk of mortality or unfavorable recovery.
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Article Synopsis
  • * Of these patients, 16 were treated with coiling and 2 with clipping, with 15 experiencing good to excellent recovery outcomes.
  • * Successful treatment relies on careful, individual, and interdisciplinary selection of patients, leading to positive radiological results and low mortality rates.
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Background: The purpose of this study was to evaluate the visual outcome after extended endoscopic endonasal transsphenoidal surgery in patients with tuberculum sellae meningiomas (TSM).

Methods: A retrospective analysis was performed for 12 patients (4 men and 8 women) with TSMs who underwent extended endonasal transsphenoidal surgery with pure endoscopy between 2003 and 2008. Neuro-ophthalmic evaluation was performed preoperatively and postoperatively.

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Background: Secondary brain damage plays a critical role in the outcome of patients with traumatic brain injury (TBI). The mechanisms underlying secondary brain damage are complex. A target that can interrupt multiple mechanisms underlying secondary brain damage may represent a promising new therapeutic approach for TBI.

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Vascular endothelial growth factor (VEGF) is a regulator of angiogenesis, vasculogenesis, and vascular permeability. Recent reports suggest that VEGF may play a critical role in formation of peritumoral brain edema (PTBE) associated with meningiomas. While VEGF expression has been shown in meningiomas, studies have not focused on VEGF in the adjacent peritumoral brain regions.

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Inflammation and immunity play a crucial role in the pathogenesis of cerebral vasospasm after subarachnoid hemorrhage (SAH). Recently, a growing body of evidence indicates that Toll-like receptor (TLR) 4 is vital for inflammation and immunity. Therefore, this study aimed to detect the expression of TLR4 in the basilar artery in a rabbit SAH model and to clarify the potential role of TLR4 in cerebral vasospasm.

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