Itolizumab Treatment for Cytokine Release Syndrome in Moderate to Severe Acute Respiratory Distress Syndrome Due to COVID-19: Clinical Outcomes, A Retrospective Study.

Background: Hyperinflammation, hypercoagulation and multi-organ dysfunction are life-threatening complications needing immediate attention in moderate-tosevere COVID-19 patients. We present our real world experience with Itolizumab, a repurposed immunomodulatory monoclonal antibody, administered in COVID-19 patients.

Methodology: Data from 25 confirmed moderate-to-severe COVID-19 patients, with high levels of pro-inflammatory markers and pulmonary function worsening on best supportive care and Itolizumab were included in this analysis.

Pulmonary Function Tests in Patients Undergoing Coronary Artery Bypass Graft Surgery and its Correlation with Outcome.

Background: Pulmonary complications are one of the most common causes of postoperative morbidity and mortality after coronary artery bypass graft (CABG) surgery. There is paucity of data of CABG in abnormal pulmonary function tests (PFT) in Indian population.

Objectives: To study correlation of PFT with clinical outcome in patients undergoing CABG.