Publications by authors named "Dina Yagel"
Am J Kidney Dis
February 2024
Article Synopsis
- This study focused on identifying genetic factors contributing to end-stage kidney disease (ESKD) in a minority group (Druze) in Israel, where existing data on genetic causes of chronic kidney disease are limited, particularly for minority populations.
- Researchers conducted whole-exome sequencing on 94 Druze patients undergoing dialysis, discovering genetic etiologies in about 18% of participants, including a novel WDR19 variant and other known genes associated with kidney disease.
- The findings highlight the importance of genetic testing in minority groups with high rates of chronic kidney disease, suggesting that certain genetic markers may go undiagnosed without comprehensive analysis, given that clinical diagnoses often did not match the final genetic results.
