Serum transglutaminase antibodies do not always detect the persistent villous atrophy in patients with celiac disease on a gluten-free diet.

Background And Aim: Serum transglutaminase antibodies (tTGs) are used for celiac disease screening and to monitor celiac disease patients on a gluten-free diet (GFD). The need for histology of duodenal biopsies to assess mucosal healing after a GFD is still a matter of debate. We evaluated whether tTGs are adequate to detect the persistence of histological lesions of duodenal mucosa in celiac patients after a GFD.

Metabolic Alterations in Celiac Disease Occurring after Following a Gluten-Free Diet.

Background And Aim: Many investigations have demonstrated that changes in body weight are frequent in patients with coeliac disease (CD) after a gluten-free diet (GFD); conversely data on the metabolic syndrome (MS) and hepatic steatosis (HS) are still rare. The aim is to evaluate the prevalence of MS and HS in patients with CD, before and after a GFD.

Methods: One hundred eighty-five coeliac adult patients were enrolled in the study.

Subtypes of chronic gastritis in patients with celiac disease before and after gluten-free diet.

Background: Celiac disease (CD) often manifests with dyspeptic symptoms and chronic gastritis is a common finding.

Aim: To evaluate the frequency of lymphocytic gastritis (LG), chronic active gastritis (CAG), and chronic inactive gastritis (CIG) in patients with CD, before and after gluten-free diet (GFD).

Methods: A five-year prospective study including all consecutive patients with a new diagnosis of CD was conducted.

Non-Celiac Gluten Sensitivity among Patients Perceiving Gluten-Related Symptoms.

Background: Non-celiac gluten sensitivity (NCGS) is a recently recognized disorder, characterized by the occurrence of symptoms following gluten ingestion. It is often self-diagnosed by the patient, but should be confirmed by the response to a gluten-free diet, followed by a gluten challenge. Celiac disease (CD) and wheat allergy (WA) must first be ruled out.