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Publications by authors named "Dina E Ghanem"

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PSORS1 Locus Genotyping Profile in Psoriasis: A Pilot Case-Control Study.
Noha Z Tawfik Hoda Y Abdallah Ranya Hassan Alaa Hosny Dina E Ghanem

Diagnostics (Basel)

April 2022

(1) Background: The psoriasis susceptibility 1 (PSORS1) locus, located within the major histocompatibility complex, is one of the main genetic determinants for psoriasis, the genotyping profile for three single-nucleotide polymorphisms (SNPs) comprising the PSORS1 locus: rs1062470 within genes, rs887466 within gene, rs10484554 within gene, were investigated and correlated with psoriasis risk and severity. (2) Methods: This pilot case-controlled study involved 100 psoriatic patients and 100 healthy individuals. We investigated three SNPs and assessed the relative gene expression profile for the gene.

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Synopsis of recent research by authors named "Dina E Ghanem"

  • - Dina E Ghanem's recent research focuses on the genetic determinants of psoriasis, specifically examining the PSORS1 locus, which is significant in understanding the susceptibility to this skin condition.
  • - In her pilot case-control study, she analyzed the genotyping profile of three single-nucleotide polymorphisms (SNPs) associated with the PSORS1 locus, comparing data from 100 psoriatic patients and 100 healthy controls.
  • - The findings aim to establish a correlation between the identified SNPs and the risk and severity of psoriasis, contributing important insights into the genetic underpinnings of this disease.

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