Trifluoromethylthiolation-arylation of diazocarbonyl compounds by modified Hooz multicomponent coupling.

A new Zn-mediated trifluoromethylthiolation-based bifunctionalization reaction is developed. In this process, simultaneous C-SCF and C-C bond formation takes place in a multicomponent reaction, in which an aryl and a SCF group arise from different reagents. Our studies show that the reaction mechanism is similar to the Hooz multicomponent coupling.