The association between the IGF-I axis, thyroid hormones and cortical bone in patients with mild primary hyperparathyroidism.

Objectives: Primary hyperparathyroidism (PHPT) is associated with low bone mineral density (BMD) and increased risk of osteoporotic fractures. This study investigated whether the IGF-I axis and thyroid hormones are associated with BMD and osteoporotic fractures before and after parathyroidectomy (PTX).

Materials And Methods: Forty-five patients with mild PHPT were examined before and 1 year after PTX.