Association of gut microbiota composition and their metabolites with subclinical atheromatosis: A systematic review.

Study Objective: The present systematic review investigates the hypothesis that specific components of the intestinal microbiome and/or their metabolites are associated with early stages of subclinical arterial damage (SAD).

Design: Based on the MOOSE criteria, we conducted a systematic review of the literature (Scopus, Medline) investigating the potential association between gut microbiota and the most widely applied arterial biomarkers of SAD.

Participants: All studies included individuals without established cardiovascular disease, either with or without SAD.