EHealth and Its Role in Supporting Audiological Rehabilitation: Patient Perspectives on Barriers and Facilitators of Using a Personal Hearing Support System With Mobile Application as Part of the EVOTION Study.

Background: Hearing loss is a major public health challenge. Audiology services need to utilise a range of rehabilitative services and maximise innovative practice afforded by technology to actively promote personalized, participatory, preventative and predictive care if they are to cope with the social and economic burden placed on the population by the rapidly rising prevalence of hearing loss. Digital interventions and teleaudiology could be a key part of providing high quality, cost-effective, patient-centred management.

A Platform for Health Record Management of the Conscripts in the Hellenic Navy.

eMass project aims to digitalize the medical examination procedure of recruitment phase of conscripts in the Hellenic Navy. eMass integrates recruits' Electronic Health Record (EHR), while allows a pre-screening test, through portable telemedicine equipment. The data will be exploited to assess the individual's cardiovascular risk through appropriate digital tools and algorithms.

Using Big Data to Develop a Clinical Decision Support System for Tinnitus Treatment.

Tinnitus is a common symptom of a phantom sound perception with a considerable socioeconomic impact. Tinnitus pathophysiology is enigmatic and its significant heterogeneity reflects a wide spectrum of clinical manifestations, severity and annoyance among tinnitus sufferers. Although several interventions have been suggested, currently there is no universally accepted treatment.

Personalized Virtual Reality Human-Computer Interaction for Psychiatric and Neurological Illnesses: A Dynamically Adaptive Virtual Reality Environment That Changes According to Real-Time Feedback From Electrophysiological Signal Responses.

Virtual reality (VR) constitutes an alternative, effective, and increasingly utilized treatment option for people suffering from psychiatric and neurological illnesses. However, the currently available VR simulations provide a predetermined simulative framework that does not take into account the unique personality traits of each individual; this could result in inaccurate, extreme, or unpredictable responses driven by patients who may be overly exposed and in an abrupt manner to the predetermined stimuli, or result in indifferent, almost non-existing, reactions when the stimuli do not affect the patients adequately and thus stronger stimuli are recommended. In this study, we present a VR system that can recognize the individual differences and readjust the VR scenarios during the simulation according to the treatment aims.

Towards a unification of treatments and interventions for tinnitus patients: The EU research and innovation action UNITI.

Tinnitus is the perception of a phantom sound and the patient's reaction to it. Although much progress has been made, tinnitus remains a scientific and clinical enigma of high prevalence and high economic burden, with an estimated prevalence of 10%-20% among the adult population. The EU is funding a new collaborative project entitled "Unification of Treatments and Interventions for Tinnitus Patients" (UNITI, grant no.

Comparison between Full Body Motion Recognition Camera Interaction and Hand Controllers Interaction used in Virtual Reality Exposure Therapy for Acrophobia.

Virtual Reality has already been proven as a useful supplementary treatment tool for anxiety disorders. However, no specific technological importance has been given so far on how to apply Virtual Reality with a way that properly stimulates the phobic stimulus and provide the necessary means for lifelike experience. Thanks to technological advancements, there is now a variety of hardware that can help enhance stronger emotions generated by Virtual Reality systems.

Emotional stimulation during motor exercise: An integration to the holistic rehabilitation framework.

Over the recent years, plenty of studies have been carried out concerning disabilities and rehabilitation. However, very few of them have focused on proposing or creating a holistic framework meant to maximize the merits of rehabilitation treatments. More importantly, an even smaller number has taken into consideration the immense impact of emotions and the crucial role they display concerning patients' performance during rehabilitation.

Utilizing Key Item Method to Manage Musculoskeletal Disorders in a Hospital Workplace.

Management of musculoskeletal disorders (MSDs) is a necessity for the modern work environment. In hospitals, these disorders have a particularly high frequency among health care workers whose work entails lifting and transporting patients as well as washing, dressing and feeding them. This paper, presents an electronic application which is based on the method of basic items (KIM - Key Item Method) in order to reduce incidents of MSDs resulting from manual transport of loads in healthcare facilities.

Evaluation for the Necessity of Medical Imaging Tests Prescription in Neurology.

The evaluation and control algorithms for the necessity of medical prescription testing, comprises useful tool for health professionals. It is beyond doubt that a connection between illness, symptoms, medical tests and prescriptions is essential and thus algorithms facilitating such approaches should be available to health professionals. Such informatics tools require the implementation of smart, interactive tools and not just linear, information storing websites.

The EVOTION Decision Support System: Utilizing It for Public Health Policy-Making in Hearing Loss.

As Decision Support Systems start to play a significant role in decision making, especially in the field of public-health policy making, we present an initial attempt to formulate such a system in the concept of public health policy making for hearing loss related problems. Justification for the system's conceptual architecture and its key functionalities are presented. The introduction of the EVOTION DSS sets a key innovation and a basis for paradigm shift in policymaking, by incorporating relevant models, big data analytics and generic demographic data.

An Internet of Things platform architecture for supporting ambient assisted living environments.

Internet of Things (IoT) is the logical further development of today's Internet, enabling a huge amount of devices to communicate, compute, sense and act. IoT sensors placed in Ambient Assisted Living (AAL) environments, enable the context awareness and allow the support of the elderly in their daily routines, ultimately allowing an independent and safe lifestyle. The vast amount of data that are generated and exchanged between the IoT nodes require innovative context modeling approaches that go beyond currently used models.

Smart adaptable system for older adults' Daily Life Activities Management - The ABLE platform.

In this paper we propose a system (ABLE) that will act as the main platform for a number of low-cost, mature technologies that will be integrated in order to create a dynamically adaptive Daily Life Activities Management environment in order to facilitate the everyday life of senior (but not exclusively) citizens at home. While the main target group of ABLE's users is the ageing population its use can be extended to all people that are vulnerable or atypical in body, intellect or emotions and are categorized by society as disabled. The classes of assistive products that are well defined in the international standard, ISO9999 such as assistive products for personal medical treatment, personal care and protection, communication, information and reaction and for personal mobility, will be easily incorporated in our proposed platform.

PAT: an intelligent authoring tool for facilitating clinical trial design.

Great investments are made by both private and public funds and a wealth of research findings is published, the research and development pipeline phases quite low productivity and tremendous delays. In this paper, we present a novel authoring tool which has been designed and developed for facilitating study design. Its underlying models are based on a thorough analysis of existing clinical trial protocols (CTPs) and eligibility criteria (EC) published in clinicaltrials.

Novel mobile-health technologies.

Mobile Health is fast becoming one of the fastest growing sectors of health as health tries to shift to patient-centric solutions. Putting the patients in the centre of care also forces them to take control of their wellbeing, health management and/or disease management. This is especially relevant when the management is constant as it is the case with chronic diseases.

A comparative study of pattern recognition classifiers to predict physical activities using smartphones and wearable body sensors.

This paper presents a wireless body area network platform that performs physical activities recognition using accelerometers, biosignals and smartphones. Multiple classifiers and sensor combinations were examined to identify the classifier with the best recognition performance for the static and dynamic activities. The Functional Trees classifier proved to provide the best results among the classifiers evaluated (Naive Bayes, Bayesian Networks, Support Vector Machines and Decision Trees [C4.

Elucidating the identity of resistance mechanisms to prednisolone exposure in acute lymphoblastic leukemia cells through transcriptomic analysis: A computational approach.

Background: It has been shown previously that glucocorticoids exert a dual mechanism of action, entailing cytotoxic, mitogenic as well as cell proliferative and anti-apoptotic responses, in a dose-dependent manner on CCRF-CEM cells at 72 h. Early gene expression response implies a dose-dependent dual mechanism of action of prednisolone too, something reflected on cell state upon 72 h of treatment.

Methods: In this work, a generic, computational microarray data analysis framework is proposed, in order to examine the hypothesis, whether CCRF-CEM cells exhibit an intrinsic or acquired mechanism of resistance and investigate the molecular imprint of this, upon prednisolone treatment.

E-Health towards ecumenical framework for personalized medicine via Decision Support System.

The purpose of the present manuscript is to present the advances performed in medicine using a Personalized Decision Support System (PDSS). The models used in Decision Support Systems (DSS) are examined in combination with Genome Information and Biomarkers to produce personalized result for each individual. The concept of personalize medicine is described in depth and application of PDSS for Cardiovascular Diseases (CVD) and Type-1 Diabetes Mellitus (T1DM) are analyzed.

Mobile phone technologies and advanced data analysis towards the enhancement of diabetes self-management.

Advances in the area of mobile and wireless communication for healthcare (m-Health) along with the improvements in information science allow the design and development of new patient-centric models for the provision of personalised healthcare services, increase of patient independence and improvement of patient's self-control and self-management capabilities. This paper comprises a brief overview of the m-Health applications towards the self-management of individuals with diabetes mellitus and the enhancement of their quality of life. Furthermore, the design and development of a mobile phone application for Type 1 Diabetes Mellitus (T1DM) self-management is presented.

2D Fast Vessel Visualization Using a Vessel Wall Mask Guiding Fine Vessel Detection.

The paper addresses the fine retinal-vessel's detection issue that is faced in diagnostic applications and aims at assisting in better recognizing fine vessel anomalies in 2D. Our innovation relies in separating key visual features vessels exhibit in order to make the diagnosis of eventual retinopathologies easier to detect. This allows focusing on vessel segments which present fine changes detectable at different sampling scales.

Using digital watermarking to enhance security in wireless medical image transmission.

Objectives: During the last few years, wireless networks have been increasingly used both inside hospitals and in patients' homes to transmit medical information. In general, wireless networks suffer from decreased security. However, digital watermarking can be used to secure medical information.

A standardised protocol for texture feature analysis of endoscopic images in gynaecological cancer.

Background: In the development of tissue classification methods, classifiers rely on significant differences between texture features extracted from normal and abnormal regions. Yet, significant differences can arise due to variations in the image acquisition method. For endoscopic imaging of the endometrium, we propose a standardized image acquisition protocol to eliminate significant statistical differences due to variations in: (i) the distance from the tissue (panoramic vs close up), (ii) difference in viewing angles and (iii) color correction.

Digital watermarking in telemedicine applications--towards enhanced data security and accessibility.

Implementing telemedical solutions has become a trend amongst the various research teams at an international level. Yet, contemporary information access and distribution technologies raise critical issues that urgently need to be addressed, especially those related to security. The paper suggests the use of watermarking in telemedical applications in order to enhance security of the transmitted sensitive medical data, familiarizes the users with a telemedical system and a watermarking module that have already been developed, and proposes an architecture that will enable the integration of the two systems, taking into account a variety of use cases and application scenarios.

Watermarking SDK implementation to facilitate integration in a secure healthcare environment.

The implementation of digital watermarking technology in healthcare applications is still in its infancy; however, the benefits of exploring this technology towards secure and efficient health data management are steadily propagated and realized by the research community. The paper presents the architecture of a watermarking software development kit (SDK), which provides multiple watermarking functionality and can be customized according to the targeted medical application, in order to address security of sensitive data, origin and data authentication, image archiving and retrieval. Two use cases of the proposed watermarking SDK are presented, the one involving access to the watermarking engine through a user interface, and the other referring to the case that the engine is embedded into the image acquisition device.

3G Networks in Emergency Telemedicine - An In-Depth Evaluation & Analysis.

The evolution of telecommunications technologies in connection with the robustness and the fidelity these new systems provide, have opened up many new horizons as regards the provision of healthcare and the quality of service from the side of the experts to that of the patients. The purpose of this paper is to evaluate the third generation telecommunications systems that are only recently being deployed in Europe, as well as argue on why a transition from 2G and 2.5G to 3G telecommunications systems could prove to be crucial, especially in relation to emergency telemedicine.

Multiple image watermarking applied to health information management.

Information technology advances have brought forth new challenges in healthcare information management, due to the vast amount of medical data that needs to be efficiently stored, retrieved, and distributed, and the increased security threats that explicitly have to be addressed. The paper discusses the perspectives of digital watermarking in a range of medical data management and distribution issues, and proposes a complementary and/or alternative tool that simultaneously addresses medical data protection, archiving, and retrieval, as well as source and data authentication. The scheme imperceptibly embeds in medical images multiple watermarks conveying patient's personal and examination data, keywords for information retrieval, the physician's digital signature for authentication, and a reference message for data integrity control.