Parvovirus B19 detection analysis in thyroid tissue paired samples: an observational study from a tertiary surgical oncology department.

Purpose: In the present study, we sought to investigate the presence of Parvovirus B19 in both abnormal and normal adjacent thyroid tissue specimens after total thyroidectomy as well as the extent that this phenomenon occurs in a population group referred to a tertiary surgical oncology department.

Methods: We detected Parvovirus B19 by Real-Time PCR in both abnormal and normal adjacent thyroid tissue specimens from 41 patients who underwent total thyroidectomy for thyroid disease (cancerous or benign). Hashimoto's thyroiditis, thyroid gland weight, maximum size of the predominant thyroid nodule as well as sex and age of the patients were also evaluated in respect to the Parvovirus B19 presence.

Patterns of Lymph Node Metastasis in Differentiated Thyroid Cancer; Clinical Implications with Particular Emphasis on the Emerging Role of Compartment-Oriented Lymph Node Dissection.

Recent advances in modern imaging allow an accurate identification of involved or suspicious lymph nodes within the nodal compartments of the neck. Careful ultrasonographic lymphatic mapping of the neck by an experienced radiologist allows a targeted, compartment-oriented (or selective) lymph node dissection to be performed instead of the more extensive modified radical lymph node dissection. Compartment-oriented lymph node dissection necessitates the close cooperation of an experienced radiologist with a particular interest in thyroid and neck ultrasonography.

Incidental thyroid C cell hyperplasia: clinical significance and implications in practice.

Incidental C cell hyperplasia (CCH) following thyroidectomy for other indications may rarely be encountered, which may raise concerns about its clinical significance and proper management. CCH can be classified as physiological (reactive) or neoplastic. Reactive CCH has no malignant potential and can be observed in association with many other thyroid diseases (including differentiated thyroid cancer); in contrast, neoplastic CCH should be considered as a preneoplastic stage in the spectrum of C cell disease, ultimately leading to the development of medullary thyroid cancer (MTC).