Are intra-tympanically administered steroids effective in patients with sudden deafness? Implications for current clinical practice.

Over 60 years since its first report, sudden sensorineural hearing loss (SSNHL) still represents an ill-explained condition, with potentially devastating effects for the quality of life of previously well patients. The present study critically reviewed the available evidence regarding the efficacy of intra-tympanic steroid administration in the treatment of SSNHL. Factors affecting that efficacy were also explored.

Diagnostic challenges and safety considerations in cochlear implantation under the age of 12 months.

Aim: To review the current knowledge on cochlear implantation in infancy, regarding diagnostic, surgical and anesthetic challenges.

Study-design: Meta-analysis. EBM level: II.