Publications by authors named "Dimitrios Asimakopoulos"
Article Synopsis
- - This study addresses the challenges of accurately segmenting airway trees in the context of diagnosing and characterizing chronic respiratory diseases, emphasizing the limitations of existing traditional methods requiring manual adjustments due to inconsistent segmentation results.
- - It introduces a novel deep learning approach called Interpolation-Split, which enhances segmentation performance by improving data quality through interpolation and image splitting, while also being efficient in terms of computational resource usage.
- - The results show that this new method significantly outperforms previous models in segmentation accuracy, achieving high dice similarity coefficients while requiring less GPU memory, making it more accessible for various computational environments.
Tissue engineering and cell therapy for regenerative medicine have great potential to treat chronic disorders. In musculoskeletal disorders, mesenchymal stromal cells (MSCs) have been identified as a relevant cell type in cell and regenerative strategies due to their multi-lineage potential, although this is likely to be a result of their trophic and immunomodulatory effects on other cells. This PRISMA systematic review aims to assess whether the age of the patient influences the chondrogenic potential of MSCs in regenerative therapy.
View Article and Find Full Text PDFObjectives: The study examined whether quantified airway metrics associate with mortality in idiopathic pulmonary fibrosis (IPF).
Methods: In an observational cohort study (n = 90) of IPF patients from Ege University Hospital, an airway analysis tool AirQuant calculated median airway intersegmental tapering and segmental tortuosity across the 2nd to 6th airway generations. Intersegmental tapering measures the difference in median diameter between adjacent airway segments.
Purpose: Bullying, harassment, and discrimination (BHD) are prevalent in academic, scientific, and clinical departments, particularly orthopedic surgery, and can have lasting effects on victims. As it is unclear how BHD affects musculoskeletal (MSK) researchers, the following study assessed BHD in the MSK research community and whether the COVID-19 pandemic, which caused hardships in other industries, had an impact.
Methods: A web-based anonymous survey was developed in English by ORS Spine Section members to assess the impact of COVID-19 on MSK researchers in North America, Europe, and Asia, which included questions to evaluate the personal experience of researchers regarding BHD.
The optimal management of hand fractures requires a multidisciplinary approach. Initial assessment should include a thorough medical history and clinical examination, followed by appropriate radiological imaging. These are crucial in determining the appropriate management.
View Article and Find Full Text PDFAutologous fat transfer is a widely used surgical technique, chosen by numerous plastic surgeons for breast augmentation surgery. This technique is based on three steps: 1. harvesting of the lipoaspirate from the patient, 2.
View Article and Find Full Text PDFThe use of mesenchymal stromal cells (MSCs) in regenerative medicine and tissue engineering is well established, given their properties of self-renewal and differentiation. However, several studies have shown that these properties diminish with age, and understanding the pathways involved are important to provide regenerative therapies in an ageing population. In this PRISMA systematic review, we investigated the effects of chronological donor ageing on the senescence of MSCs.
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