Comparison of contemporary transcatheter heart valve prostheses: data from the German Aortic Valve Registry (GARY).

Background: Various second-generation transcatheter heart valve (THV) prostheses with high clinical efficacy and safety are available, but there is limited large-scale data available comparing their hemodynamic performance and clinical implications.

Objective: To compare the hemodynamic performance and short-term clinical outcome of four second-generation THV prostheses.

Methods: 24,124 patients out of the German Aortic Valve Registry who underwent transfemoral transcatheter aortic valve implantation (TAVI) (Evolut™ R n = 7028, Acurate neo™ n = 2922, Portico n = 878 and Sapien 3 n = 13,296) were included in this analysis.