Publications by authors named "Dimitri Kornblum"
Whether severe COVID-19 is by itself a significant risk factor for the development of candidemia currently remains an open question as conflicting results have been published. We aim to assess the occurrence of candidemia in patients with severe COVID-19 admitted to the intensive care unit (ICU). We conducted a retrospective study on patients with severe SARS-CoV-2-related pneumonia admitted to 5 ICUs in France who were specifically screened for fungal complications between March 2020 and January 2021.
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- A quinquagenarian patient with AIDS and fungal endocarditis developed a nosocomial thrombophlebitis in the right jugular vein, which was treated with a combination of antibiotics and therapeutic anticoagulation, leading to a recovery without recurrence after 12 months.
- The case highlights the challenges of treating septic thrombophlebitis, particularly due to the lack of standardized treatment protocols and concerns about multidrug-resistant bacteria.
- The findings suggest that effective management should involve removing any medical devices, using appropriate antibiotic therapy for at least six weeks, and administering anticoagulation for a similar duration to reduce bacterial load and minimize resistance.
The worldwide emergence of multidrug-resistant pathogenic fungi is a threat to human health. At this very moment, an emergence of isolates harbouring a resistance to fluconazole, one of the most popular antifungal drugs, is being described in several countries. We seek to better understanding the epidemiology, pathogenicity and transmission of resistant Faced with an outbreak of invasive infections due to resistant isolates of , we performed a 7-year retrospective and prospective analysis of 283 isolates collected in 240 patients, among who 111 had invasive candidiasis.
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