Homocysteine levels and lacunar brain infarcts in elderly women: the prospective population study of women in Gothenburg.

Objectives: To examine whether total serum homocysteine (tHcy) in a population-based sample of middle-aged women is an independent risk factor for presence of lacunar infarcts (LIs) 24 years later.

Design: Prospective population study, follow-up time 24 years.

Setting: Gothenburg, an urban area in western Sweden.

Serum homocysteine in relation to mortality and morbidity from coronary heart disease: a 24-year follow-up of the population study of women in Gothenburg.

Background: Elevated serum total homocysteine (tHcy) is an established risk factor for cardiovascular disease (CVD), especially in men. However, there are few prospective population studies on female cohorts, and none of these has been longer than 13 years.

Methods And Results: The Population Study of Women in Gothenburg began in 1968/1969, at which time a representative population-based cohort of women aged 38, 46, 50, 54, and 60 years was recruited.

Participation bias in longitudinal studies: experience from the Population Study of Women in Gothenburg, Sweden.

Objective: To describe a cohort study of women receiving a series of comprehensive health examinations over 32 years.

Design: Longitudinal population study based on a randomised sample of the female population from defined age cohorts.

Setting: City of Göteborg, Sweden.