Digital manufacturing techniques and the in vitro biocompatibility of acrylic-based occlusal device materials.

Objectives: Material chemistry and workflow variables associated with the fabrication of dental devices may affect the biocompatibility of the dental devices. The purpose of this study was to compare digital and conventional workflow procedures in the manufacturing of acrylic-based occlusal devices by assessing the cytotoxic potential of leakage products.

Methods: Specimens were manufactured by 3D printing (stereolithography and digital light processing), milling, and autopolymerization.