Publications by authors named "Dimelza Arauz"

Article Synopsis
  • - Panama has experienced endemic Dengue virus (DENV) transmission since 1993, with all four serotypes present but no local DENV-4 cases reported since 2000, despite its ongoing circulation in nearby countries.
  • - In the last four months of 2023, DENV-4 was detected in Panama, coinciding with a rise in dengue cases during the typically dry season, which is unusual since outbreaks are usually seen during the rainy season.
  • - Analysis of complete DENV-4 genomes revealed that the recent cases were due to genotype IIb, the same as what was seen 23 years ago, showing the need for ongoing surveillance of dengue serotypes and genotypes to catch emerging variants early.
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During a molecular screening of rickettsial, borrelial and protozoal agents in ticks from rural areas of Panama, we detected DNA of Rickettsia amblyommatis in four Amblyomma mixtum collected from horses in a locality in Los Santos province. Ehrlichia minasensis and Anaplasma marginale were identified from three and two Rhipicephalus microplus, respectively, collected on cows from Chiriqui province. No DNA from other tick-borne agents was found.

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Article Synopsis
  • Eastern equine encephalitis virus (EEEV), Madariaga virus (MADV), and Venezuelan equine encephalitis virus complex (VEEV) are mosquito-borne viruses that cause febrile and neurological diseases in humans and horses.
  • Researchers developed real-time reverse transcription PCR assays to detect these viruses using whole-genome sequences and validated them with various samples collected during outbreaks and surveillance in Panama.
  • The assays successfully identified VEEV complex RNA in a significant number of samples, revealing its presence even in suspected dengue cases, indicating their potential use for surveillance in endemic areas.
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We report a case of reinfection by SARS-CoV-2 with the second virus harboring amino acid changes in the Spike protein (141-143del, D215A, ins215AGY, L452R, D614G), orf1a, helicase, orf3a, and Nucleocapside. The virus associated with the reinfection, from an endemic lineage containing the S:L452R immune escape mutation, was circulating in Panama at the time.

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There is limited evidence regarding severe acute respiratory syndrome coronavirus 2 infection in the placenta of pregnant women who tested positive, and if this could be a route for vertical transmission of the virus in utero. We present the cases of 2 pregnant women in their third trimester who were admitted for delivery by cesarean delivery and who, through universal screening, tested positive for coronavirus disease 2019. The maternal and fetal sides of the placenta were sectioned from both patients for viral analysis.

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Zika virus (ZIKV) was first detected in the Americas in Brazil in 2015, with a rapid spread to surrounding countries. In Panama, the outbreak began in November 2015 in an indigenous community located on the Caribbean side of the country. Zika virus is typically associated with a diffuse rash, fever, and conjunctivitis.

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Background: Chikungunya virus (CHIKV) typically causes explosive epidemics of fever, rash and polyarthralgia after its introduction into naïve populations. Since its introduction in Panama in May of 2014, few autochthonous cases have been reported; most of them were found within limited outbreaks in Panama City in 2014 and Puerto Obaldia town, near the Caribbean border with Colombia in 2015. In order to confirm that Panama had few CHIKV cases compared with neighboring countries, we perform an epidemiological analysis of chikungunya cases reported from May 2014 to July 2015.

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Chikungunya virus (CHIKV) is a mosquito-borne pathogen that was only endemic in Africa and south Asia until 2005 and 2006, when the virus spread into the Indian Ocean islands, Europe, and Asia. Autochthonous CHIKV transmission in the Caribbean islands was reported in December of 2013. In Panama, two febrile cases were detected in May of 2014: one traveling from Haiti, and the other traveling from the Dominican Republic.

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