Biological characterization of epimastigotes derived from trypomastigotes isolated from Brazilian chagasic patients.

Chagas disease (CD), caused by , occurs in several countries in Latin America and non-endemic countries. Heterogeneity among population has been the Achilles' heel to find a better treatment for CD. In this study, we characterized the biochemical parameters and mitochondrial bioenergetics of epimastigotes differentiated from eight  isolates (I1-I8) obtained from Brazilian CD patients.