Submicrometre spatiotemporal characterization of the Toxoplasma adhesion strategy for gliding motility.

Toxoplasma gondii is a protozoan apicomplexan parasite that uses an adhesion-dependent mode of motility termed gliding to access host cells and disseminate into tissues. Previous studies on Apicomplexa motile morphotypes, including the T. gondii tachyzoite, have identified a cortical actin-myosin motor system that drives the rearward translocation of transmembrane adhesins, thus powering forward movement.

Body mass index and risk of surgical site infection following spine surgery: a meta-analysis.

Purpose: Inconsistent results have been reported in the literature on the association between obesity, expressed as increased body mass index (BMI), and risk for surgical site infection (SSI) following spine surgery. The objective of this study was to review and quantify the association between increased BMI and risk of spinal SSI in adults.

Methods: We performed a comprehensive search for relevant studies using PubMed, Embase, and references of published manuscripts.