Publications by authors named "Dilip Kumar Yadav"
Article Synopsis
- Neonatal mortality is a significant global health issue that reflects the effectiveness of maternal and child health services, and this study aimed to identify factors associated with neonatal mortality in Nepal.
- The study followed 1,104 babies (368 low birth weight and 736 normal weight) for 28 days after birth, revealing a neonatal mortality rate of 10 per 1,000 live births.
- Key factors linked to higher neonatal mortality included fathers with no formal education, multiple pregnancies, and low APGAR scores at 5 minutes, suggesting that improving education and access to healthcare could enhance neonatal outcomes.
Intraosseous Lipoma of Calcaneus An Uncommon Cause of Heel Pain: A Case Report.
JNMA J Nepal Med Assoc
April 2024
Article Synopsis
- Intraosseous lipoma of the calcaneum is a rare condition that can cause significant heel pain, particularly in younger adults, with limited published cases.
- A 35-year-old woman experienced worsening left heel pain for a year, which was severe enough to impact her daily activities; she underwent surgery involving curettage and bone cement filling.
- Post-surgery follow-up showed no residual pain after 2.5 years, highlighting the need for orthopedic surgeons to consider this uncommon diagnosis and the effectiveness of surgical treatment when conservative methods fail.
Cellular metabolism plays an essential role in the regrowth and regeneration of a neuron following physical injury. Yet, our knowledge of the specific metabolic pathways that are beneficial to neuron regeneration remains sparse. Previously, we have shown that modulation of O-linked β-N-acetylglucosamine (O-GlcNAc) signaling, a ubiquitous post-translational modification that acts as a cellular nutrient sensor, can significantly enhance in vivo neuron regeneration.
View Article and Find Full Text PDFUnlabelled: Synovial chondromatosis in association with ankylosing spondylitis is extremely rare and has been reported only once before and this case report is presenting a similar case. The knee is the preferential site of involvement with involvement of the hip being reported sparsely. We herein report a case of a 52-year-old male who came with complaints of the lower back pain for 5 years and left hip pain for 1.
View Article and Find Full Text PDFMaternal and Obstetric Factors Associated with Low Birth Weight.
J Nepal Health Res Counc
January 2020
Background: Low birth weight is a factor associated with perinatal, neonatal and post-neonatal morbidity and mortality and is associated with development of chronic diseases in adulthood. This study aimed to identify the maternal and obstetric factors associated with low birth weight in selected hospitals of Nepal.
Methods: Matched case control study was conducted in two tertiary level hospital of Nepal during May 2017 to April 2018.
Background: Mounting evidence suggests that nutritional exposures during pregnancy influence the fetal epigenome, and that these epigenetic changes can persist postnatally, with implications for disease risk across the life course.
Methods: We review human intergenerational studies using a three-part search strategy. Search 1 investigates associations between preconceptional or pregnancy nutritional exposures, focusing on one-carbon metabolism, and offspring DNA methylation.