Publications by authors named "Dilip Kumar Shanmugam"
Hydrogels are a promising material for a variety of applications after appropriate functional and structural design, which alters the physicochemical properties and cell signaling pathways of the hydrogels. Over the past few decades, considerable scientific research has made breakthroughs in a variety of applications such as pharmaceuticals, biotechnology, agriculture, biosensors, bioseparation, defense, and cosmetics. In the present review, different classifications of hydrogels and their limitations have been discussed.
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- Microgreens are young plants harvested from various food crops, typically within 7-21 days, known for their rich nutrients, strong flavors, and vibrant colors.
- They are increasingly popular among chefs and nutrition researchers for their health benefits, including vitamins and bioactive compounds that may help prevent malnutrition and chronic diseases.
- The article emphasizes the potential of microgreens to promote healthier diets and combat health issues associated with modern sedentary lifestyles.
The development of biocompatible nanocomposite hydrogels with effective wound healing/microbicidal properties is needed to bring out their distinguished characteristics in clinical applications. The positive interaction between graphene oxide/reduced graphene oxide (GO/rGO) and hydrogels and aloe vera gel represents a strong strategy for the advancement of therapeutic approaches for wound healing. In this study, the synthesis, characterization, and angiogenic properties of graphene-based nanocomposite gels have been corroborated and substantiated through several in vitro and in vivo assays.
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- - Mucormycosis is increasingly linked to COVID-19, prompting the term "COVID-19 associated mucormycosis (CAM)", which is particularly concerning in India due to high COVID-19 cases with co-morbidities.
- - Treatment is complicated by antifungal resistance and delayed symptoms after COVID-19 recovery, making early diagnosis critical to improve outcomes and reduce morbidity and mortality.
- - The main treatment involves Amphotericin B and surgical debridement, but there are challenges with toxicity and surgery; thus, alternative therapies are explored to enhance treatment efficacy and reduce duration.
Regenerative medicine, a therapeutic approach using stem cells, aims to rejuvenate and restore the normalized function of the cells, tissues, and organs that are injured, malfunctioning, and afflicted. This influential technology reaches its zenith when it is integrated with the CRISPR-Cas (clustered regularly interspaced short palindromic repeats-CRISPR associated) technology of genome editing. This tool acts as a programmable restriction enzyme system, which targets DNA as well as RNA and gets redeployed for the customization of DNA/RNA sequences.
View Article and Find Full Text PDFThe rising global population and their food habits result in food wastage and cause an obstacle in its treatment and disposal. Due to the rapid shift in the lifestyle of the human population and urbanization, almost one-third of the food produced is wasted from various sectors like domestic sources, agricultural sectors, and industrial sectors. These food resources squandered are rich in organic biomolecules which can cause complications upon direct disposal in the environment.
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