Publications by authors named "Dilip Kapur"

Article Synopsis
  • * The study utilized proteomics and multiglycomics to analyze cerebrospinal fluid from patients receiving long-term intrathecal morphine or baclofen, revealing conserved proteomic and N-glycomic profiles.
  • * Significant differences in polysialic acids, heparan sulfate glycosaminoglycans, and O-glycans were found between the two treatment groups, highlighting new molecular effects of opioids on pain management.
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Study Objectives: The use of opioid medication for chronic pain has been increasing. The main aim of this study was to assess how many patients on opioids for chronic pain had sleep disordered breathing (SDB) and the type of SDB. The impact of these medications on daytime arterial blood gas (ABG) measurements and psychomotor vigilance was also studied.

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Pain acceptance contributes significantly to the effectiveness of pain treatment outcomes. Nevertheless, little research has been conducted to examine whether a decrease in acceptance contributes to a deterioration in post treatment functioning. The aim of this study was to assess the role of pain acceptance in relation to process and outcome variables in the six-months following the conclusion of a pain program.

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Background: Recently, an 8-item short-form version of the Chronic Pain Acceptance Questionnaire (CPAQ-8) was developed predominantly in an internet sample. Further investigation of the factor structure in a multidisciplinary pain clinic sample is required. Investigation of the concurrent validity of the CPAQ-8 after accounting for the effects of variables commonly measured in the pain clinic setting is also necessary.

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Occupation-related musculoskeletal disorders are a common clinical problem. Management presents challenges in understanding the factors that give rise to work loss and disability. To improve outcomes, practitioners need to screen for risk factors, understand the demands of work and workplaces and be prepared to actively assist the process of work return.

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Neuropathic pain and diabetes.

Diabetes Metab Res Rev

September 2003

Neuropathic pain is a common phenomenon resulting from injury to the central or peripheral nervous system. The means by which diabetes results in nerve injury is unclear but the effect is to cause injury at all levels of the nervous system from the level of the peripheral nerves to the brain. Nerve injury causes pain through a cascade of mechanisms resulting in altered processing of sensory input into the nervous system.

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