Single-cell transcriptomes reveal the heterogeneity and microenvironment of vestibular schwannoma.

Background: Vestibular schwannoma (VS) is the most common benign tumor in the cerebellopontine angle and internal auditory canal. Illustrating the heterogeneous cellular components of VS could provide insights into its various growth patterns.

Methods: Single-cell RNA sequencing was used to profile transcriptomes from 7 VS samples and 2 normal nerves.

Rehabilitative management of pelvic fractures needs to be further optimized.

We read with interest the review by Piccione et al. into the rehabilitative management of patients with pelvic fracture (PF). This review adds to our knowledge about the significance and indispensability of early multidisciplinary intervention in PF.