Publications by authors named "Diler Ali Sarper"

Article Synopsis
  • The study investigates the link between the ACTN3 R577X gene and sarcopenia in Turkish adults aged 65 and older, an issue common in geriatrics.
  • It involved 197 participants, measuring various health metrics, with findings indicating no strong association between the gene polymorphism and indicators of sarcopenia.
  • The research suggests that gender may influence low muscle mass more significantly than the ACTN3 gene, highlighting the need for further research on ethnic impacts on muscle health in older populations.
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The frequency and the distribution of HLA-B27 subtypes in spondylarthropathy (SpA) patients and controls were investigated in a sample Turkish population. B27 subtyping was performed by PCR-SSP method in two groups: 49 unrelated HLA-B27 positive Turkish patients with the diagnosis of SpA according to the European Spondyloarthropathy Study Group Criteria, and 55 HLA-B27 positive healthy controls. The frequency of HLA-B*27 was 2.

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We report a positive association between HLA-DRB1*15 (p= 0.0002) in Turkish patients with pediatric severe aplastic anemia (SAA) and a paradoxically favorable influence of the susceptibility marker on the clinical response to immunosuppressive therapy. These findings point to an immune mechanism mediated by DRB1*15 in SAA which confers responsiveness to treatment.

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