Publications by authors named "Dilara S Khoshknabi"
Objectives: Total joint arthroplasties are among the most common elective procedures performed in the United States, and they are associated with postoperative pain. Gabapentin enacarbil is a prodrug with an extended-release formulation that has been proposed for multimodal postoperative analgesia, but the drug's efficacy for major arthroplasties remains unclear.
Materials And Methods: We enrolled 60 adult patients scheduled for primary knee or hip arthroplasty expected to remain hospitalized for at least 3 days.
Methylphenidate side effects in advanced cancer: a retrospective analysis.
Am J Hosp Palliat Care
February 2010
Introduction: Methylphenidate (MP) is often recommended for symptom control in advanced cancer. Little is known about its side effects in frail adults.
Objectives: To evaluate MP-associated symptoms or side effects (S/E).
Article Synopsis
- A patient with multiple lung cancers experienced severe cancer-related fatigue (CRF) and was treated with methylphenidate, starting at 5 mg twice daily and increasing to 10 mg after two weeks.
- After maintaining the 10 mg dosage for 8 months, the patient showed significant improvement in her CRF as measured by the Brief Fatigue Inventory score.
- This improvement in fatigue was linked to the normalization of neurophysiologic measurements, indicating a potential benefit of methylphenidate in managing CRF in cancer patients.