Publications by authors named "Dilan Barut"
Article Synopsis
- Bacterial membrane vesicles (BMVs) serve as key communication tools between bacteria and host cells, showing potential as smart drug delivery systems (SDDSs) for transporting therapeutic agents.
- The review discusses the design, characteristics, and methods for producing, purifying, and loading drugs into BMVs, along with their mechanisms for drug release and their applications in anticancer and antimicrobial therapies.
- It emphasizes the need for safety assessments and highlights challenges for clinical use, while also addressing recent advancements and the future potential of BMVs in nanomedicine and targeted drug delivery.
For cost-competitive biosynthesis of polyhydroxybutyrate (PHB), the screening of efficient producers and characterization of their genomic potential is fundamental. In this study, 94 newly isolated halophilic strains from Turkish salterns were screened for their polyhydroxyalkanoates (PHAs) biosynthesis capabilities through fermentation. Halomonas halmophila 18H was found to be the highest PHB producer, yielding 63.
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- This study investigates the outer membrane vesicles (OMVs) of a halophilic bacterium (KB2) under varying salt concentrations (6%, 12%, and 18%) to understand their role in stress adaptation.
- Findings reveal that while OMV production increases when salinity decreases, OMVs may not directly contribute to the bacterium's adaptation to increased salt stress, as the cells exhibit structural and metabolic stability instead.
- Comparative analysis with a mesophilic bacterium highlights different proteome profiles, suggesting distinct adaptive mechanisms to salinity between these species.
Bacterial membrane vesicles (BMVs) are cupped-shaped structures formed by bacteria in response to environmental stress, genetic alteration, antibiotic exposure, and others. Due to the structural similarities shared with the producer organism, they can retain certain characteristics like stimulating immune responses. They are also able to carry molecules for long distances, without changes in the concentration and integrity of the molecule.
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