Photobiomodulation in Ophthalmology: A Comprehensive Review of Bench-to-Bedside Research and Clinical Integration.

Photobiomodulation (PBM), also known as low-level laser therapy, is an emerging therapeutic modality in ophthalmology, attracting increasing interest for its potential to manage a variety of ocular conditions. PBM employs low-energy light within the red and near-infrared spectrum to penetrate biological tissues, where it interacts with cellular chromophores. This interaction is believed to enhance mitochondrial function, boost adenosine triphosphate (ATP) production, and reduce oxidative stress, leading to improved cellular repair and tissue regeneration.

Limitations of effective medium models for tissue phantoms in the THz frequency range.

The absorption of terahertz (THz) radiation by water molecules facilitates its application to several biomedical applications such as cancer detection. Therefore, it is critical for the THz technologies to be characterised with water content in a sample. In this paper, we analyse gelatine phantoms in the THz frequency range, with continuously varying hydration levels as they dry over time.

A Comprehensive Review on Acanthamoeba Keratitis: An Overview of Epidemiology, Risk Factors, and Therapeutic Strategies.

keratitis (AK) is a rare but severe corneal infection caused by the free-living amoeba, , which is ubiquitously present in the environment. This condition predominantly affects contact lens wearers but can also occur in non-lens users, particularly those exposed to contaminated water or with compromised immune systems. AK is characterized by progressive corneal inflammation, epithelial defects, and ulceration, which can lead to significant visual impairment or blindness if not promptly diagnosed and treated.

Ultrafast dynamics of fluorene initiated by highly intense laser fields.

We present an investigation of the ultrafast dynamics of the polycyclic aromatic hydrocarbon fluorene initiated by an intense femtosecond near-infrared laser pulse (810 nm) and probed by a weak visible pulse (405 nm). Using a multichannel detection scheme (mass spectra, electron and ion velocity-map imaging), we provide a full disentanglement of the complex dynamics of the vibronically excited parent molecule, its excited ionic states, and fragments. We observed various channels resulting from the strong-field ionization regime.

Cutting edge tools in the field of soil microbiology.

The study of the whole of the genetic material contained within the microbial populations found in a certain environment is made possible by metagenomics. This technique enables a thorough knowledge of the variety, function, and interactions of microbial communities that are notoriously difficult to research. Due to the limitations of conventional techniques such as culturing and PCR-based methodologies, soil microbiology is a particularly challenging field.

Recent Strategies for the Remediation of Textile Dyes from Wastewater: A Systematic Review.

The presence of dye in wastewater causes substantial threats to the environment, and has negative impacts not only on human health but also on the health of other organisms that are part of the ecosystem. Because of the increase in textile manufacturing, the inhabitants of the area, along with other species, are subjected to the potentially hazardous consequences of wastewater discharge from textile and industrial manufacturing. Different types of dyes emanating from textile wastewater have adverse effects on the aquatic environment.

Addressing three-body fragmentation of methane dication using "native frames": Evidence of internal excitation in fragments.

The three body fragmentation of methane dication has been studied using the technique of cold target recoil ion momentum spectroscopy. The process is initiated by impact of energetic Ar9+ ions on neutral methane and the data is subsequently collected in coincidence with Ar8+ projectile. By analysing the dissociation channels leading to (H + H+ + CH2+) and (H + H2+ + CH+) fragments, it is concluded that these fragments are formed in a sequential manner via formation of molecular intermediates CH3+ and CH2+ respectively.

Oscillatoria sancta Cultivation Using Fruit and Vegetable Waste Formulated Media and Its Potential as a Functional Food: Assessment of Cultivation Optimization.

The most cost-effective technique to cultivate microalgae is with low-cost resources, like fruit and vegetable peels. This study examined the viability of culturing microalgae (Oscillatoria sancta PCC 7515) isolated from a waterlogged region of Punjab, India, in a low-cost medium (fruit and vegetable waste peels) for pharmaceutical use. 16S rRNA sequencing discovered O.

Nano-Biofertilizer Formulations for Agriculture: A Systematic Review on Recent Advances and Prospective Applications.

In the twenty-first century, nanotechnology has emerged as a potentially game-changing innovation. Essential minerals are mostly unavailable in modern cropping systems without the application of synthetic fertilizers, which have a serious negative impact on the ecosystem. This review focuses on the coupling of nanoparticles with biofertilizers to function as nano-biofertilizers (NBFs), which may ensure world food security in the face of the rising population.

Revolutionizing biofuel generation: Unleashing the power of CRISPR-Cas mediated gene editing of extremophiles.

Molecular biology techniques like gene editing have altered the specific genes in micro-organisms to increase their efficiency to produce biofuels. This review paper investigates the outcomes of Clustered regularly interspaced short palindromic repeats (CRISPR) for gene editing in extremophilic micro-organisms to produce biofuel. Commercial production of biofuel from lignocellulosic waste is limited due to various constraints.

Transformation of Agro-Waste into Value-Added Bioproducts and Bioactive Compounds: Micro/Nano Formulations and Application in the Agri-Food-Pharma Sector.

The agricultural sector generates a significant amount of waste, the majority of which is not productively used and is becoming a danger to both world health and the environment. Because of the promising relevance of agro-residues in the agri-food-pharma sectors, various bioproducts and novel biologically active molecules are produced through valorization techniques. Valorization of agro-wastes involves physical, chemical, and biological, including green, pretreatment methods.

Molecularly Imprinted Polymer-Based Electrochemical Sensor for Rapid and Selective Detection of Hypoxanthine.

In this paper, we report on the coupling of an electrochemical transducer with a specifically designed biomimetic and synthetic polymeric layer that serves as a recognition surface that demonstrates the molecular memory necessary to facilitate the stable and selective identification of the meat-freshness indicator hypoxanthine. Consumer preferences and the food safety of meat products are largely influenced by their freshness, so it is crucial to monitor it so as to quickly identify when it deteriorates. The sensor consists of a glassy-carbon electrode, which can be regenerated in situ continuously, functionalized with molecularly imprinted polymers (MIPs) and a nanocomposite of curcumin-coated iron oxide magnetic nanospheres (C-IO-MNSs) and multiwalled carbon nanotubes (MWCNTs) that enhance the surface area as well as the electroactive characteristics.

Recent Strategies for Bioremediation of Emerging Pollutants: A Review for a Green and Sustainable Environment.

Environmental pollution brought on by xenobiotics and other related recalcitrant compounds have recently been identified as a major risk to both human health and the natural environment. Due to their toxicity and non-biodegradability, a wide range of pollutants, such as heavy metals, polychlorinated biphenyls, plastics, and various agrochemicals are present in the environment. Bioremediation is an effective cleaning technique for removing toxic waste from polluted environments that is gaining popularity.

Characterization of novel euryhaline microalgal cultures from Punjab, India for bioactive compounds.

Microalgae have gained recognition due to the occurrence of nutraceuticals which are sustainable reservoir to substitute the organic chemical-based health supplements. The biomass of microalgae incorporates various functional biomolecules like chlorophyll, carotenoids and phenols that exhibit therapeutic properties and act as nutraceuticals. In spite of the higher production of the microalgal biomass, difference in their biochemical composition, and lack of characterization for nutraceutical properties are the prime hindrance in upscaling these bio-factories.

Unexplained dissociation pathways of two-body fragmentation of methane dication.

The ion-induced fragmentation of CH into H and CH is studied using a cold target recoil ion momentum spectroscopy in coincidence with the charge state of the post-collision projectile. Using constant velocity Ar and N, results from four different datasets are presented, with a selection on the final charge state of the projectile (Ar or Ar and N or N). Three distinct dissociation pathways (I, II, and III) are observed for each dataset, with the mean kinetic energy release values of around 4.

Dual spectroscopic detection of THz energy modes of critical chemical compounds.

Precise identification and sensing of organic and inorganic molecular systems are key factors in several applications in present industrial and scientific domains. While high energy modes, due to electronic interactions, are mostly impervious to the initial thermodynamic or chemical conditions, the low energy modes are sensitive to such alterations which makes them suitable for quality control purpose with sensitive spectral identification methods. Here we report for the first time, several low frequency peaks of specific nitrogen-based compounds and their derivatives, using the dual spectroscopic approach of Terahertz Time-Domain Spectroscopy (THz-TDS) and THz Raman Spectroscopy (THz-RS).

Review on recent advances in fabrication of enzymatic and chemical sensors for hypoxanthine.

Hypoxanthine is an important product of the nucleotide degradation pathway. It has been considered as a potential marker for assessing meat freshness and clinical diagnosis. In the review, we focus on advancement made in the fabrication of hypoxanthine sensors.

Critical spectroscopic considerations towards reliable detection of material using terahertz time-domain spectroscopy.

Terahertz (THz) time-domain spectroscopic (TDS) and imaging techniques have been recognized as important tools in recent times for non-contact and non-destructive evaluation of materials, such as, food, pharmaceuticals, and other composite materials of interest. The application of the THz-TDS technique in both material identification and quantification, however, involves the analyses of extremely complex response of the constituents of these composite materials. For a spectroscopist, therefore, it is essential to consider certain critical spectroscopic parameters while acquiring the spectroscopic data using THz-TDS.