Fever of unknown origin and Q-fever: a case series in a Bulgarian hospital.

Background: Fever of unknown origin (FUO) is a perplexing medical problem. The causes for FUO are more than 200 diseases. The aim of the study was to present human clinical cases of infection debuting as FUO.

Quantitative expediency assessment of the zeta sedimentation ratio and the plasma viscosity in arterial hypertension research.

Accepted methods of the ESR methodology (the Westergren mode and ZSR mode) and its alternative the plasma viscosity were tested for diagnostic utility in pregnancy induced hypertension and pre-eclampsia. The receiver-operating characteristic curve (ROC) analysis approved moderate diagnostic accuracy for the ESR methodology and supplied support for its preliminary estimated cutoff values but failed to indicate cogent discernment of pathology by values of plasma viscosity. Likely pathological whole blood alterations boost the erythrocyte aggregation while the concomitant depletion of macromolecules degrades plasma viscosity values.

Serum sperm antibodies after diarrhoeal diseases.

The origin of 'natural' anti-sperm antibodies found in fertile humans, virgin girls, and boys before puberty, is quite obscure. One hypothetical mechanism relates their existence to inflammatory gastrointestinal entities: as a result of the disease, cross-reactive antibodies produced against gastrointestinal flora bind spermatozoa. To test this assumption, we evaluated the level of serum sperm antibodies after diarrhoeal infections.

[Prevention of neural tube defects with folic acid].

Neural Tube Defects (NTD's) include a large number of congenital malformations produced when the open neural tube presents a very early stages in the development of the human embryo fails to close on or before the first month post conception. NTD's are considered to be one of the most common forms of malformations with varying degrees depending of genetic and environmental conditions. The studies prove that the additional taken of folic acid plays an important role against the NTD's.

[Prophylaxis with tercef of infection-related complications after cesarean section].

The purpose of this prospective and case controlled study is to determine the effectiveness and safety of antibiotic prophylaxis with Tercef (ceftriaxone) in women undergoing cesarean section and to compare the results with those of 24 hours regiment of Cefazolin and also with a group without prophylaxis. The study includes 122 cases of elective and emergency CS: 41 with a single intravenous dose of 1.0 g Tercef after clamping of the umbilical cord; 41 cases of antibiotic prophylaxis with Cefazolin three times 2.

Serum sperm antibodies are not elevated after mumps orchitis.

Objective: To assess the level of serum sperm antibodies after mumps orchitis.

Design: Controlled descriptive study.

Setting: Academic research environment.

[Hemorheological parameters in the prognosis of the risk of fetal retardation in pregnancy with arterial hypertension].

The haemorheological theory creates the notions of the interrelationship between the haemodynamic alterations in the blood flow and the whole-blood viscosity. The whole-blood viscosity is a variable parameter in close relation to the vessel geometry and blood flow rate, the blood plasma viscosity, the volume concentration of the blood cells, mostly of the red blood cells (the haematocrit) as well as to the hydrodynamically effective haemorheological phenomena of the aggregation and deformability of the erythrocytes. In the onward development of pregnancy in Bulgarian women with pre-eclamptic signs an increase of the haematocrit, the haemoglobin concentration and the erythrocyte aggregation were found.

[The medicosocial aspects of contraception for teenagers].

The authors study and examine the influence of some medical and social factors on the teenagers use of contraceptives. The study is based on the questionnaires fulfill by 568 teenagers (aged 13-19). In the enquêtes are shown the role of the family status of the parents the involvement of the family and the school in the sex education, and also are indicated the favorite teenager's contraceptive methods.

[The incidence of clinical forms of female endocrine sterility in 1990-1993 at the III Gynecological Clinic of the Maternity Home of the State Institutional Hospital].

The high frequency of the female endocrine sterility and the favorable therapy results are showing categorically the importance of the endocrine sterility as a medical and a social problem. For the period 1990-1993 in Third Gynaecological clinic--Sector of Gynaecological Endocrinology, were observed 584 patients with proved endocrine sterility. The present research has the goal to discuss the frequency of the different clinical forms of the endocrine sterility.

[The use of the triphasic contraceptive preparation trisiston for therapeutic purposes].

After a brief review of the qualities of the new triphasic contraceptive preparation Trisistone and some of its advantages in comparison with the other combined contraceptive drugs the authors report on the results from the first study, carried out in our country, on the therapeutic effect of Trisistone. Thirty-eight women with various gynecological diseases were treated. The largest group was that of women with irregular bleedings.

[Our experience in using the triphasic contraceptive trisiston for contraception].

The authors carried out studies on 80 women, using Trisistone, a preparation of Germed, Jenapharm, DDR, in the course of 250 cycles, taking into consideration the advantages of triphasic contraceptive preparations as well as the fact that till this moment there were not applied in our country. A good contraceptive efficiency was established. No case with conception was recorded.

[Diagnostic and therapeutic problems in typhoid fever complicated by severe enterorrhagia (apropos a patient successfully treated by surgery)].

The case history of a 69-year-old patient with typhoid fever is described. The disease ran an atypical course; with early jaundice syndrome, severe enterorrhagia and late appearance of roseola. He was successfully treated by surgical intervention--hemicolectomy.